INT149120

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.14
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (CTLA4, Cd28) Golgi apparatus (CTLA4)
Anatomy Link Frequency
T cells 1
CTLA4 (Homo sapiens)
Cd28 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Arthritis 1 50.00 Quite Low
Inflammation 1 46.96 Quite Low
abatacept 1 26.00 Quite Low
rheumatoid arthritis 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Cancer 1 68.16 Quite High
Necrosis 1 67.60 Quite High
Arthritis 1 50.00 Quite Low
INFLAMMATION 1 46.96 Quite Low
Rheumatoid Arthritis 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
CTLA-4 is a regulator of co-stimulation and inhibits the activation of T cells through interfering with the interaction of CD80/86 on antigen-presenting cells with CD28 on T cells.
CTLA-4 Binding (interaction) of CD28 in T cells
1) Confidence 0.03 Published 2008 Journal Ann. Rheum. Dis. Section Abstract Doc Link 18203760 Disease Relevance 0.14 Pain Relevance 0

General Comments

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