INT149138

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Context Info
Confidence 0.37
First Reported 2002
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 27
Total Number 27
Disease Relevance 32.62
Pain Relevance 9.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PDX1) generation of precursor metabolites and energy (PDX1) nucleus (PDX1)
cytoplasm (PDX1)
Anatomy Link Frequency
granulocyte 1
covering 1
connective 1
face 1
lobe 1
PDX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
fibrosis 3613 100.00 Very High Very High Very High
Inflammation 185 99.56 Very High Very High Very High
corticosteroid 100 98.16 Very High Very High Very High
Inflammatory response 4 93.40 High High
cva 11 84.52 Quite High
palliative 50 80.52 Quite High
Tendonitis 2 77.64 Quite High
Thoracotomy 23 66.52 Quite High
cINOD 2 61.04 Quite High
Pain 12 54.04 Quite High
Disease Link Frequency Relevance Heat
Idiopathic Pulmonary Fibrosis 2796 100.00 Very High Very High Very High
Pulmonary Fibrosis 987 100.00 Very High Very High Very High
Disease 566 100.00 Very High Very High Very High
Bronchiolitis Obliterans Organizing Pneumonia 109 100.00 Very High Very High Very High
Nicotine Addiction 79 100.00 Very High Very High Very High
INFLAMMATION 178 99.56 Very High Very High Very High
Cirrhosis 11 98.24 Very High Very High Very High
Hyperplasia 10 97.32 Very High Very High Very High
Fibrosis 274 96.72 Very High Very High Very High
Metastasis 29 96.40 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ingestion dose coefficients were calculated as 2.8 x 10(-8), 2.1 x 10(-8), 2.5 x 10(-8) and 3.8 x 10(-8) Sv Bq(-1) for ICRP, SENES, TBM and GSF model parameters, respectively.
GSF Binding (2.8) of
1) Confidence 0.37 Published 2008 Journal Radiat Environ Biophys Section Abstract Doc Link 18204850 Disease Relevance 0.33 Pain Relevance 0
Cigarette smoking is strongly associated with IPF.
IPF Binding (associated) of associated with fibrosis and nicotine addiction
2) Confidence 0.36 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2330030 Disease Relevance 1.67 Pain Relevance 0.55
Meanwhile, cigarette smoking is consistently associated with IPF.
IPF Binding (associated) of associated with fibrosis and nicotine addiction
3) Confidence 0.36 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2330030 Disease Relevance 1.80 Pain Relevance 0.57
IPF is associated with a pathological lesion known as usual interstitial pneumonia (UIP).
IPF Binding (associated) of associated with fibrosis and idiopathic pulmonary fibrosis
4) Confidence 0.36 Published 2008 Journal Orphanet J Rare Dis Section Abstract Doc Link PMC2330030 Disease Relevance 2.07 Pain Relevance 0.48
Some environmental factors may be associated with IPF (cigarette smoking, exposure to silica and livestock).
IPF Binding (associated) of associated with fibrosis and nicotine addiction
5) Confidence 0.36 Published 2008 Journal Orphanet J Rare Dis Section Abstract Doc Link PMC2330030 Disease Relevance 1.81 Pain Relevance 0.45
AE-IPF is recognized by clinical criteria established in the first published case series from Japan [24].
AE-IPF Binding (recognized) of associated with fibrosis
6) Confidence 0.36 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2330030 Disease Relevance 1.83 Pain Relevance 0.63
IPF is recognized on high-resolution computed tomography by peripheral, subpleural lower lobe reticular opacities in association with subpleural honeycomb changes.
IPF Binding (recognized) of in lobe associated with fibrosis
7) Confidence 0.36 Published 2008 Journal Orphanet J Rare Dis Section Abstract Doc Link PMC2330030 Disease Relevance 1.81 Pain Relevance 0.46
The histopathological lesion associated with IPF is known as usual interstitial pneumonia (UIP).
IPF Binding (associated) of associated with fibrosis and idiopathic pulmonary fibrosis
8) Confidence 0.36 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2330030 Disease Relevance 0.87 Pain Relevance 0.24
Questionnaires were mailed to the GP or nurse named by the practice as its coordinator of GSF implementation, with a covering letter.
GSF Binding (implementation) of in covering
9) Confidence 0.34 Published 2009 Journal Quality & Safety in Health Care Section Body Doc Link PMC2685539 Disease Relevance 0.21 Pain Relevance 0.24
The results were compared with values calculated by applying our GSF parameters (GSF).
GSF Binding (applying) of
10) Confidence 0.32 Published 2008 Journal Radiat Environ Biophys Section Abstract Doc Link 18204850 Disease Relevance 0.31 Pain Relevance 0.05
The results were compared with values calculated by applying our GSF parameters (GSF).
GSF Binding (applying) of
11) Confidence 0.32 Published 2008 Journal Radiat Environ Biophys Section Abstract Doc Link 18204850 Disease Relevance 0.32 Pain Relevance 0.05
CONCLUSION: This study goes some way towards untangling aspects of facilitation associated with successful implementation of the GSF.
GSF Binding (implementation) of
12) Confidence 0.32 Published 2010 Journal Fam Pract Section Body Doc Link 19875747 Disease Relevance 0 Pain Relevance 0
ngn3, Pdx1, and Hb9 are essential factors for mammalian ?
Pdx1 Binding (factors) of
13) Confidence 0.29 Published 2005 Journal PLoS Medicine Section Body Doc Link PMC1087208 Disease Relevance 0.17 Pain Relevance 0
Microscopic honeycombs do not equate with the UIP pattern nor do they connote a diagnosis of IPF.
IPF Binding (diagnosis) of associated with fibrosis and idiopathic pulmonary fibrosis
14) Confidence 0.28 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2330030 Disease Relevance 2.21 Pain Relevance 0.39
The development of AE-IPF in patients without known IPF can be recognized when consensus criteria for IPF (see below) are satisfied and the patient presents with acute respiratory failure.
AE-IPF Binding (recognized) of in respiratory associated with fibrosis and respiratory failure
15) Confidence 0.28 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2330030 Disease Relevance 2.17 Pain Relevance 0.72
Living with IPF also made patients reflect on their lives and their emotional selves.
IPF Binding (Living) of associated with fibrosis
16) Confidence 0.28 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1276807 Disease Relevance 0.70 Pain Relevance 0.21
If these instruments were used to evaluate IPF patients over time, their inclusion of items that cover less relevant topics may introduce variance into patients' scores that would tend to obscure, rather than reveal, changes in quality of life specifically associated with IPF or its therapy.
IPF Binding (associated) of associated with fibrosis
17) Confidence 0.28 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1276807 Disease Relevance 1.09 Pain Relevance 0.44
While many patients recognized this positive aspect that living with IPF had on their relationships with their spouses and family members, several patients mentioned how the effects of this disease caused a great deal of tension between them and their loved ones.
IPF Binding (living) of associated with fibrosis and disease
18) Confidence 0.28 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1276807 Disease Relevance 0.84 Pain Relevance 0.24
Several patients felt like friends could not understand all that living with IPF entails.
IPF Binding (living) of associated with fibrosis
19) Confidence 0.28 Published 2005 Journal Health Qual Life Outcomes Section Body Doc Link PMC1276807 Disease Relevance 0.89 Pain Relevance 0.22
After adjusting for age and sex, this cohort demonstrated a strong association between smoking and IPF (odds ratio [OR], 3.6; 95% confidence interval [CI], 1.3–9.8).
IPF Binding (association) of associated with fibrosis and nicotine addiction
20) Confidence 0.27 Published 2008 Journal Orphanet J Rare Dis Section Body Doc Link PMC2330030 Disease Relevance 1.68 Pain Relevance 0.54

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