INT14916

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Context Info
Confidence 0.37
First Reported 1981
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 15
Total Number 15
Disease Relevance 13.64
Pain Relevance 1.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RASA1) signal transduction (RASA1) plasma membrane (RASA1)
embryo development (RASA1) cytoplasm (RASA1)
Anatomy Link Frequency
pancreas 1
lamina 1
posterior 1
RASA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Trigeminal neuralgia 4 99.18 Very High Very High Very High
headache 8 97.28 Very High Very High Very High
cva 40 95.52 Very High Very High Very High
Pain 8 92.20 High High
Dismenorea 1 91.56 High High
fifth nerve 1 82.36 Quite High
drug abuse 57 80.32 Quite High
anesthesia 20 70.16 Quite High
imagery 12 67.80 Quite High
antagonist 2 66.40 Quite High
Disease Link Frequency Relevance Heat
Arterial-venous Cerebral Malformations 65 100.00 Very High Very High Very High
Brain Tumor 20 99.98 Very High Very High Very High
Hemorrhage 50 99.96 Very High Very High Very High
Cerebral Aneurysm 6 99.74 Very High Very High Very High
Aneurism 22 99.64 Very High Very High Very High
Headache 13 99.18 Very High Very High Very High
Convulsion 8 96.84 Very High Very High Very High
Paresis 4 96.08 Very High Very High Very High
Brain Hemorrhage 16 95.80 Very High Very High Very High
Cv General 4 Under Development 12 95.52 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This paper reports a case of meningioma associated with AVM.
AVM Binding (associated) of associated with arterial-venous cerebral malformations and brain tumor
1) Confidence 0.37 Published 1986 Journal No Shinkei Geka Section Abstract Doc Link 3703119 Disease Relevance 1.11 Pain Relevance 0.09
[A meningioma associated with AVM: a case report].
AVM Binding (associated) of associated with arterial-venous cerebral malformations and brain tumor
2) Confidence 0.37 Published 1986 Journal No Shinkei Geka Section Title Doc Link 3703119 Disease Relevance 1.20 Pain Relevance 0.09
One of these mRNAs encodes the gap junction protein connexin26, known as a tumor suppressor, which was 10.8- and 6.9-fold more abundant in pancreatic carcinoma than in normal pancreas and chronic pancreatitis, respectively.
gap Binding (abundant) of in pancreas
3) Confidence 0.36 Published 2004 Journal Pancreas Section Body Doc Link 15502644 Disease Relevance 0.18 Pain Relevance 0
We propose that the formation of gap junctions may be stimulated by some physiologic change.
gap Binding (formation) of
4) Confidence 0.35 Published 1981 Journal Am. J. Obstet. Gynecol. Section Abstract Doc Link 7246625 Disease Relevance 0.19 Pain Relevance 0.09
In addition, we think that the aneurysms of the left occipital artery on the side ipsilateral to the AVM may have originated from the site of the arterial wall lacking the internal elastic lamina and developed due to hemodynamic mechanism associated with the AVM.
AVM Binding (associated) of in lamina associated with aneurism and arterial-venous cerebral malformations
5) Confidence 0.31 Published 1981 Journal No Shinkei Geka Section Abstract Doc Link 7290322 Disease Relevance 1.12 Pain Relevance 0.10
CONCLUSIONS: Our data suggest a significant interaction of patient age and clinical and morphological AVM features and argue against uniform AVM characteristics across different age classes at initial presentation.
AVM Binding (interaction) of
6) Confidence 0.27 Published 2003 Journal Stroke Section Body Doc Link 14576378 Disease Relevance 0.11 Pain Relevance 0
Only two cases of meningioma associated with AVM have been reported.
AVM Binding (associated) of associated with arterial-venous cerebral malformations and brain tumor
7) Confidence 0.27 Published 1986 Journal No Shinkei Geka Section Abstract Doc Link 3703119 Disease Relevance 1.32 Pain Relevance 0.09
It is quite rare that cerebral tumor associates with intracranial AVM.
AVM Binding (associates) of associated with arterial-venous cerebral malformations and brain tumor
8) Confidence 0.27 Published 1986 Journal No Shinkei Geka Section Abstract Doc Link 3703119 Disease Relevance 1.15 Pain Relevance 0.09
As a result, adapter proteins such as Grb2, Ras-specific GTPase-activating protein (GAP), and phosphatidylinositol-3-kinase (PI-3K), can interact with the phosphotyrosine residues and stimulate downstream signaling, including the Ras-MAPK and PI-3K-Akt pathways.
GAP Binding (interact) of
9) Confidence 0.13 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721306 Disease Relevance 0 Pain Relevance 0.03
As a result, adapter proteins such as Grb2, Ras-specific GTPase-activating protein (GAP), and phosphatidylinositol-3-kinase (PI-3K), can interact with the phosphotyrosine residues and stimulate downstream signaling, including the Ras-MAPK and PI-3K-Akt pathways.
GTPase-activating protein Binding (interact) of
10) Confidence 0.12 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721306 Disease Relevance 0 Pain Relevance 0.03
Posterior fossa AVMs causing trigeminal neuralgia in the literature are reviewed, and the association of the AVM and the aneurysm in the posterior fossa is also discussed.
AVM Binding (association) of in posterior associated with trigeminal neuralgia, aneurism and arterial-venous cerebral malformations
11) Confidence 0.11 Published 1990 Journal Neurol. Med. Chir. (Tokyo) Section Abstract Doc Link 1709477 Disease Relevance 1.35 Pain Relevance 0.39
0.95) and one (or more) GAP ?
GAP Binding (0.95) of
12) Confidence 0.04 Published 2006 Journal PLoS ONE Section Body Doc Link PMC1762434 Disease Relevance 0.15 Pain Relevance 0.13
With increasing availability of endoscopy and elective angiography AVM is being more frequently recognized.
AVM Binding (recognized) of associated with arterial-venous cerebral malformations
13) Confidence 0.01 Published 2009 Journal World J Emerg Surg Section Body Doc Link PMC2687422 Disease Relevance 1.42 Pain Relevance 0.07
With increasing use of angiography over the past 30 years in the assessment of gastrointestinal bleeding, AVM has been more frequently recognized [3].
AVM Binding (recognized) of associated with hemorrhage and arterial-venous cerebral malformations
14) Confidence 0.01 Published 2009 Journal World J Emerg Surg Section Body Doc Link PMC2687422 Disease Relevance 2.18 Pain Relevance 0.06
A cerebral aneurysm may also be associated with the AVM.
AVM Binding (associated) of associated with cerebral aneurysm and arterial-venous cerebral malformations
15) Confidence 0.00 Published 2010 Journal Anesthesiology Research and Practice Section Body Doc Link PMC2911602 Disease Relevance 2.17 Pain Relevance 0.18

General Comments

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