INT149244

Context Info Confidence 0.49 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Abstract Documents 1 Total Number 1 Disease Relevance 0.72 Pain Relevance 0.40

aging (Aqp2) plasma membrane (Aqp2) protein complex (Aqp2) transmembrane transport (Aqp2) lysosome (Aqp2) cytoplasm (Aqp2)

Anatomy Link Frequency kidney 2 Aqp2 (Rattus norvegicus)

Pain Link Frequency Relevance Heat COX-2 inhibitor 5 93.00 cINOD 3 80.64

Disease Link Frequency Relevance Heat Polyuria 3 94.28 Diabetes Insipidus 7 90.96 INFLAMMATION 1 54.72

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Semiquantitative immunoblotting using whole-kidney homogenates revealed that COX-2 inhibition caused significant increases in the abundance of AQP2 and NKCC2.

Positive_regulation (increases) of Localization (abundance) of AQP2 in kidney

1) Confidence 0.49 Published 2008 Journal Am. J. Physiol. Renal Physiol. Section Abstract Doc Link 18216147 Disease Relevance 0.72 Pain Relevance 0.40

General Comments

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