INT149259

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Context Info
Confidence 0.67
First Reported 2005
Last Reported 2011
Negated 5
Speculated 0
Reported most in Body
Documents 38
Total Number 39
Disease Relevance 15.73
Pain Relevance 3.87

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
knee 2
plasma 1
corpus 1
tibia 1
internal 1
RCT (Mus musculus)
Pain Link Frequency Relevance Heat
complementary and alternative medicine 393 99.80 Very High Very High Very High
Osteoarthritis 86 99.80 Very High Very High Very High
agonist 65 99.46 Very High Very High Very High
Pain 160 99.04 Very High Very High Very High
imagery 87 98.60 Very High Very High Very High
Angina 16 93.48 High High
antagonist 8 87.52 High High
backache 60 85.76 High High
Botox 21 81.04 Quite High
Acupuncture 224 80.32 Quite High
Disease Link Frequency Relevance Heat
Rotator Cuff Tears 127 100.00 Very High Very High Very High
Disorder Of Lipid Metabolism 931 99.98 Very High Very High Very High
Osteoarthritis 85 99.80 Very High Very High Very High
Pain 166 99.04 Very High Very High Very High
Pneumonia 167 98.84 Very High Very High Very High
Scoliosis 35 98.24 Very High Very High Very High
Coronary Artery Disease 33 98.08 Very High Very High Very High
Cognitive Disorder 14 96.88 Very High Very High Very High
Disease 100 96.76 Very High Very High Very High
Acute Cholecystitis 17 96.64 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Seven RCT were selected, with 349 patients.
Gene_expression (selected) of RCT
1) Confidence 0.67 Published 2008 Journal Gastroenterol Hepatol Section Body Doc Link 18218271 Disease Relevance 0 Pain Relevance 0
With the requirements of regulatory bodies such as the Food and Drug Administration in the USA, the RCT has been not only expected but mandated in the pharmaceutical area.
Gene_expression (expected) of RCT
2) Confidence 0.53 Published 2009 Journal Trials Section Body Doc Link PMC2654883 Disease Relevance 0.06 Pain Relevance 0.06
Furthermore, the accuracy of ultrasound examination in previously operated shoulders was investigated in a recent study of Prickett et al. [23], who showed sensitivity of 91% and specificity of 86% for detection of RCT, generally comparable to those of MRI investigations [27].
Gene_expression (detection) of RCT in shoulders associated with rotator cuff tears and imagery
3) Confidence 0.53 Published 2010 Journal J Orthop Traumatol Section Body Doc Link PMC2837810 Disease Relevance 1.15 Pain Relevance 0.44
The highest impact innovations should be prioritised for RCT evaluation where such an evaluation is ethical and feasible.
Gene_expression (evaluation) of RCT
4) Confidence 0.53 Published 2009 Journal Trials Section Body Doc Link PMC2654883 Disease Relevance 0 Pain Relevance 0
Hence, results of the RCT may not be applicable to such workplaces.
Gene_expression (results) of RCT
5) Confidence 0.52 Published 2010 Journal BMC Med Res Methodol Section Body Doc Link PMC2895606 Disease Relevance 0 Pain Relevance 0
Macrophage-to-feces RCT is unchanged in exercising mice
Neg (unchanged) Gene_expression (unchanged) of RCT in feces
6) Confidence 0.52 Published 2010 Journal Nutr Metab (Lond) Section Body Doc Link PMC2903598 Disease Relevance 0.37 Pain Relevance 0.06
The increase in cholesterol efflux in vitro was not reflected by altered plasma counts in the in vivo RCT experiment, likely since these represent the net balance between efflux and removal from the plasma compartment.
Gene_expression (experiment) of RCT in plasma
7) Confidence 0.52 Published 2010 Journal Nutr Metab (Lond) Section Body Doc Link PMC2903598 Disease Relevance 0.59 Pain Relevance 0.11
Aim of this RCT is to demonstrate that H can decrease the conversion rate compared to MD in LC for AC, without a significant increase of morbidity.
Gene_expression (Aim) of RCT associated with acute cholecystitis
8) Confidence 0.49 Published 2009 Journal Trials Section Abstract Doc Link PMC2693511 Disease Relevance 0.58 Pain Relevance 0.03
At first, serious doubts about this RCT were expressed, particularly regarding the willingness of IS patients to go through the process of randomization.
Gene_expression (expressed) of RCT associated with scoliosis
9) Confidence 0.46 Published 2008 Journal BMC Musculoskelet Disord Section Body Doc Link PMC2386134 Disease Relevance 0.71 Pain Relevance 0
DAF and HM conducted the RCT and analysed the data.
Gene_expression (conducted) of RCT
10) Confidence 0.42 Published 2007 Journal BMC Public Health Section Body Doc Link PMC1868722 Disease Relevance 0.47 Pain Relevance 0
We perform a series of analyses on a corpus of randomly selected collection of RCT abstracts to answer the following questions:
Gene_expression (abstracts) of RCT in corpus
11) Confidence 0.30 Published 2008 Journal BMC Med Inform Decis Mak Section Body Doc Link PMC2584633 Disease Relevance 0 Pain Relevance 0
The RCT and CAM
Gene_expression (The) of RCT associated with complementary and alternative medicine
12) Confidence 0.25 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952302 Disease Relevance 0 Pain Relevance 0.18
Evaluating the RCT
Gene_expression (Evaluating) of RCT
13) Confidence 0.25 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952302 Disease Relevance 0.10 Pain Relevance 0.17
Before discussing the RCT in detail, it is important to identify limitations to the effectiveness of the RCT in measuring the efficacy of interventions in medical science generally.
Gene_expression (discussing) of RCT
14) Confidence 0.25 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2952302 Disease Relevance 0 Pain Relevance 0.09
There are four types of biases that occur during the conduct of an RCT that affect internal validity: a) Selection bias: biased allocation to comparison groups, b) Performance bias: unequal provision of care apart from treatment under evaluation, c) Detection bias: biased assessment of outcome and d) Attrition bias: biased occurrence and handling of deviations from protocol and loss to follow-up.[18]
Gene_expression (conduct) of RCT in internal
15) Confidence 0.18 Published 2007 Journal Indian Journal of Urology : IJU : Journal of the Urological Society of India Section Body Doc Link PMC2721595 Disease Relevance 0 Pain Relevance 0
In order to assess whether an intervention has the same effect in a relevant clinical population as it does in an RCT, comparative studies in pragmatically selected cohorts are essential.
Gene_expression (does) of RCT
16) Confidence 0.18 Published 2006 Journal BMC Med Res Methodol Section Body Doc Link PMC1540434 Disease Relevance 0.20 Pain Relevance 0
An important question not answered by an RCT is that of clinical applicability: Are the effect sizes observed in an RCT reduplicated in an open clinical study?
Gene_expression (observed) of RCT
17) Confidence 0.18 Published 2006 Journal BMC Med Res Methodol Section Body Doc Link PMC1540434 Disease Relevance 0.23 Pain Relevance 0.16
A selection bias might have been introduced in the RCT assessing arthroscopy surgery for osteoarthritis of the knee because 44% of the eligible patients declined to participate in the study.
Gene_expression (introduced) of RCT in knee associated with osteoarthritis
18) Confidence 0.18 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1800311 Disease Relevance 0.10 Pain Relevance 0.16
Antiatherogenesis: RCT
Gene_expression (Antiatherogenesis) of RCT
19) Confidence 0.17 Published 2010 Journal Vascular Health and Risk Management Section Body Doc Link PMC2988622 Disease Relevance 1.31 Pain Relevance 0
The RCT was introduced in exactly this context initially [2,3,8,9].
Gene_expression (introduced) of RCT
20) Confidence 0.16 Published 2006 Journal BMC Med Res Methodol Section Body Doc Link PMC1540434 Disease Relevance 0 Pain Relevance 0.04

General Comments

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