INT149291

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.40
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.64
Pain Relevance 0.84

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NRP1) cytosol (NRP1) signal transduction (NRP1)
extracellular region (NRP1) cell adhesion (NRP1) plasma membrane (NRP1)
Anatomy Link Frequency
cleavage 1
lung 1
NRP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Infliximab 12 98.52 Very High Very High Very High
cINOD 6 93.68 High High
rheumatoid arthritis 81 89.00 High High
Abeta 9 87.04 High High
Inflammation 56 77.04 Quite High
Inflammatory marker 3 44.00 Quite Low
cytokine 9 5.00 Very Low Very Low Very Low
methotrexate 6 5.00 Very Low Very Low Very Low
visual analogue scale 3 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adult Respiratory Distress Syndrome 28 99.84 Very High Very High Very High
Congenital Anomalies 1 96.00 Very High Very High Very High
INFLAMMATION 63 93.28 High High
Cognitive Disorder 1 92.16 High High
Hypercalcemia 51 91.24 High High
Rheumatoid Arthritis 81 89.00 High High
Alzheimer's Dementia 2 82.32 Quite High
Disease 68 78.64 Quite High
Targeted Disruption 2 77.84 Quite High
Necrosis 3 73.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We found that VEGF165b was widely expressed in normal healthy lung tissue but is reduced in ARDS lung.
Negative_regulation (reduced) of VEGF165b in lung associated with adult respiratory distress syndrome
1) Confidence 0.40 Published 2010 Journal American Journal of Physiology - Lung Cellular and Molecular Physiology Section Abstract Doc Link PMC2886605 Disease Relevance 0.62 Pain Relevance 0
These toxic effects are likely due to inhibition of Notch cleavage, a transmembrane receptor involved in regulating cell-fate decisions.
Negative_regulation (inhibition) of transmembrane receptor in cleavage
2) Confidence 0.05 Published 2008 Journal Curr Top Med Chem Section Abstract Doc Link 18220933 Disease Relevance 0.93 Pain Relevance 0.44
In contrast, 1CTP did not seem to decrease as much as P1NP indicating that the reduced bone formation in the P-group was not balanced by the reduced 1CTP.
Negative_regulation (decrease) of P1NP
3) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656227 Disease Relevance 0.37 Pain Relevance 0.15
In the P-group, mainly reduced levels of P1NP and 1CTP correlated with changes in BMD at both skeletal sites.
Negative_regulation (reduced) of P1NP
4) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656227 Disease Relevance 0.33 Pain Relevance 0.10
This means that the reduction of P1NP levels in the P-group was balanced by the decrease in CTX-1.
Negative_regulation (reduction) of P1NP
5) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2656227 Disease Relevance 0.38 Pain Relevance 0.16

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox