INT149293

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.93
Pain Relevance 0.44

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (NRP1) cytosol (NRP1) signal transduction (NRP1)
extracellular region (NRP1) cell adhesion (NRP1) plasma membrane (NRP1)
Anatomy Link Frequency
cleavage 2
NRP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cINOD 3 93.68 High High
Abeta 9 87.04 High High
Disease Link Frequency Relevance Heat
Congenital Anomalies 1 96.00 Very High Very High Very High
INFLAMMATION 1 93.28 High High
Cognitive Disorder 1 92.16 High High
Alzheimer's Dementia 2 82.32 Quite High
Disease 4 78.64 Quite High
Targeted Disruption 2 77.84 Quite High
Brain Disease 1 63.68 Quite High
Toxicity 2 25.00 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These toxic effects are likely due to inhibition of Notch cleavage, a transmembrane receptor involved in regulating cell-fate decisions.
Negative_regulation (inhibition) of Protein_catabolism (cleavage) of transmembrane receptor in cleavage
1) Confidence 0.05 Published 2008 Journal Curr Top Med Chem Section Abstract Doc Link 18220933 Disease Relevance 0.93 Pain Relevance 0.44

General Comments

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