INT149315

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Context Info
Confidence 0.04
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0
Pain Relevance 0.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Gnaq) signal transduction (Gnaq) plasma membrane (Gnaq)
GTPase activity (Gnaq) protein complex (Gnaq) signal transducer activity (Gnaq)
Gnaq (Mus musculus)
Pain Link Frequency Relevance Heat
Glutamate receptor 1 100.00 Very High Very High Very High
cocaine 3 96.32 Very High Very High Very High
Serotonin 8 64.52 Quite High
Opioid 3 56.92 Quite High
Dopamine 8 44.76 Quite Low
agonist 25 44.68 Quite Low
antagonist 6 42.80 Quite Low
Potency 4 5.00 Very Low Very Low Very Low
opioid receptor 2 5.00 Very Low Very Low Very Low
Enkephalin 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 4 5.00 Very Low Very Low Very Low
Osteoporosis 1 5.00 Very Low Very Low Very Low
Bordatella Infection 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low
Coronary Heart Disease 1 5.00 Very Low Very Low Very Low
Influenza Virus Infection 1 5.00 Very Low Very Low Very Low
Hydrocephalus 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A decrease in regulator of G protein signaling 4 levels may weaken its interactions with metabotropic glutamate receptor 5, Galphaq, and phospholipase C beta that may enhance drug-induced signaling.
Galphaq Binding (interactions) of associated with glutamate receptor
1) Confidence 0.04 Published 2008 Journal J. Neurochem. Section Abstract Doc Link 18221378 Disease Relevance 0 Pain Relevance 0.20
Ligand-specific Gq signaling in Rs1
Gq Binding (Ligand) of
2) Confidence 0.04 Published 2007 Journal PLoS ONE Section Body Doc Link PMC2267039 Disease Relevance 0 Pain Relevance 0.06

General Comments

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