INT149344

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Kcnab1, Kcna1) transmembrane transport (Kcnab1, Kcna1) cytoplasm (Kcnab1)
Anatomy Link Frequency
neuronal 1
Kcnab1 (Mus musculus)
Kcna1 (Mus musculus)
Pain Link Frequency Relevance Heat
Neuronal excitability 2 99.22 Very High Very High Very High
Hippocampus 1 88.44 High High
Spinal cord 1 73.12 Quite High
hyperexcitability 1 29.04 Quite Low
Neuropathic pain 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Convulsion 1 76.64 Quite High
Disease 1 5.00 Very Low Very Low Very Low
Neuropathic Pain 1 5.00 Very Low Very Low Very Low
Epilepsy 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To reduce neuronal excitability, screening for compounds that prevent inactivation of Kv1.1 channels by Kvbeta1 was performed using a yeast two-hybrid screen.
Kvbeta1 Positive_regulation (inactivation) of Kv1 in neuronal associated with neuronal excitability
1) Confidence 0.01 Published 2008 Journal Bioorg. Med. Chem. Section Abstract Doc Link 18226531 Disease Relevance 0.08 Pain Relevance 0.18

General Comments

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