INT149386

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Context Info
Confidence 0.40
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.14
Pain Relevance 0.91

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Lyn, TRPV4) Golgi apparatus (Lyn) enzyme binding (Lyn)
transmembrane transport (TRPV4) cytoplasm (Lyn) signal transduction (Lyn)
Anatomy Link Frequency
sensory neurons 1
Lyn (Mus musculus)
TRPV4 (Homo sapiens)
Pain Link Frequency Relevance Heat
Hyperalgesia 7 96.76 Very High Very High Very High
Mechanotransduction 1 95.28 Very High Very High Very High
Inflammation 1 87.52 High High
vincristine 2 87.20 High High
intrathecal 1 82.00 Quite High
peripheral neuropathy 1 73.64 Quite High
Pain 2 72.76 Quite High
nociceptor 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Hyperalgesia 7 96.76 Very High Very High Very High
Targeted Disruption 1 89.16 High High
Diabetes Mellitus 2 87.72 High High
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 78.96 Quite High
Alcohol Addiction 1 75.76 Quite High
Peripheral Neuropathy 1 73.64 Quite High
Pain 1 62.20 Quite High
Nervous System Injury 1 5.00 Very Low Very Low Very Low
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, we establish a direct interaction between TRPV4, alpha2 integrin, and the Src tyrosine kinase Lyn in sensory neurons.
Lyn Binding (interaction) of TRPV4 in sensory neurons
1) Confidence 0.40 Published 2008 Journal J. Neurosci. Section Abstract Doc Link 18234883 Disease Relevance 1.14 Pain Relevance 0.91

General Comments

This test has worked.

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