INT149429

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.38
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (ERCC2) aging (ERCC2) chromosome segregation (ERCC2)
intracellular (IL8) helicase activity (ERCC2) extracellular matrix organization (ERCC2)
Anatomy Link Frequency
EM-2 2
ERCC2 (Homo sapiens)
IL8 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 8 50.00 Quite Low
Osteoarthritis 8 50.00 Quite Low
Endogenous opioid 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 8 67.80 Quite High
Osteoarthritis 8 67.52 Quite High
INFLAMMATION 4 63.80 Quite High
Arthritis 4 50.00 Quite Low
Pain 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EM-2 inhibited IL-8 secretion only from RA tissue (maximum 10(-10)M).
EM-2 Negative_regulation (inhibited) of Localization (secretion) of IL-8 in EM-2
1) Confidence 0.05 Published 2008 Journal Arthritis Rheum. Section Body Doc Link 18240240 Disease Relevance 0.18 Pain Relevance 0
EM-1 inhibited synovial secretion of IL-6 in patients with RA and secretion of IL-8 in patients with RA and those with OA (maximum 10(-10)M).
EM-1 Negative_regulation (inhibited) of Localization (secretion) of IL-8
2) Confidence 0.05 Published 2008 Journal Arthritis Rheum. Section Body Doc Link 18240240 Disease Relevance 0.20 Pain Relevance 0

General Comments

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