INT149513

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Context Info
Confidence 0.53
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.79
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Trpv3)
Trpv3 (Mus musculus)
Pain Link Frequency Relevance Heat
Spinal cord 1 98.96 Very High Very High Very High
qutenza 5 98.48 Very High Very High Very High
agonist 1 98.04 Very High Very High Very High
Nerve growth factor 1 83.60 Quite High
allodynia 1 69.20 Quite High
fifth nerve 2 62.40 Quite High
Neuropathic pain 1 60.72 Quite High
Pain 1 52.40 Quite High
TRP channel 13 50.00 Quite Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 9 99.84 Very High Very High Very High
Hypothermia 1 85.04 High High
Neuropathic Pain 2 69.20 Quite High
Hypersensitivity 1 68.08 Quite High
Brain Injury 2 25.08 Quite Low
Loss Of Sense Of Smell 4 24.08 Low Low
Apoptosis 2 10.60 Low Low
Death 3 8.92 Low Low
Necrosis 1 5.00 Very Low Very Low Very Low
Injury 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the pathological condition, the expression of TRPV3, TRPV4, TRPM5, and TRPA1 was markedly reduced and recovery took a long time.
Negative_regulation (reduced) of Gene_expression (expression) of TRPV3
1) Confidence 0.53 Published 2010 Journal Acta Oto-Laryngologica Section Body Doc Link PMC2981077 Disease Relevance 0 Pain Relevance 0.13
Unexpectedly, TRPV3 mRNA expression was upregulated in shRNAtg but downregulated in knockout mice.
Negative_regulation (downregulated) of Gene_expression (expression) of TRPV3 associated with targeted disruption
2) Confidence 0.41 Published 2008 Journal Mol. Cell. Neurosci. Section Abstract Doc Link 18249134 Disease Relevance 0.79 Pain Relevance 0.47

General Comments

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