INT14961

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Context Info
Confidence 0.30
First Reported 1989
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 3.42
Pain Relevance 1.70

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pf4) extracellular region (Pf4) protein complex assembly (Pf4)
molecular_function (Pf4) protein complex (Pf4)
Anatomy Link Frequency
platelet 6
plasma 2
Pf4 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Angina 19 99.28 Very High Very High Very High
Inflammation 11 95.76 Very High Very High Very High
cva 1 51.60 Quite High
ischemia 4 41.04 Quite Low
imagery 6 5.00 Very Low Very Low Very Low
Versed 3 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 35 99.84 Very High Very High Very High
Angina 11 99.28 Very High Very High Very High
Cv General 3 Under Development 9 97.52 Very High Very High Very High
INFLAMMATION 12 95.76 Very High Very High Very High
Apoptosis 22 82.08 Quite High
Coronary Artery Disease 5 75.00 Quite High
Thrombosis 2 75.00 Quite High
Cv Unclassified Under Development 3 41.04 Quite Low
Infarction 7 35.52 Quite Low
Cicatrix 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Mean platelet factor 4(PF4) levels measured in 10 cases of each subgroup were significantly elevated in myocardial infarction (MI) (48.4 +/- 15.16 ng/ml) and III unstable angina patients (44.7 +/- 15.9 ng/ml) as compared to controls (25.42 +/- 12.47 ng/ml; P less than 0.01).
Positive_regulation (elevated) of Gene_expression (levels) of platelet factor 4 in platelet associated with angina and myocardial infarction
1) Confidence 0.30 Published 1990 Journal Indian Heart J Section Abstract Doc Link 1711506 Disease Relevance 0.92 Pain Relevance 0.34
Mean platelet factor 4(PF4) levels measured in 10 cases of each subgroup were significantly elevated in myocardial infarction (MI) (48.4 +/- 15.16 ng/ml) and III unstable angina patients (44.7 +/- 15.9 ng/ml) as compared to controls (25.42 +/- 12.47 ng/ml; P less than 0.01).
Positive_regulation (elevated) of Gene_expression (levels) of PF4 in platelet associated with angina and myocardial infarction
2) Confidence 0.30 Published 1990 Journal Indian Heart J Section Abstract Doc Link 1711506 Disease Relevance 0.91 Pain Relevance 0.33
On the other hand, the plasma levels of BTG and PF4 were increased in patients with variant angina as compared with those with stable exertional angina but did not show a significant circadian variation in both groups.
Positive_regulation (increased) of Gene_expression (levels) of PF4 in plasma associated with angina
3) Confidence 0.27 Published 1989 Journal Circulation Section Abstract Doc Link 2532074 Disease Relevance 0.84 Pain Relevance 0.87
This proinflammatory effect was combined with an enhanced expression of proangiogenic Platelet factor 4.
Positive_regulation (enhanced) of Gene_expression (expression) of Platelet factor 4 in Platelet
4) Confidence 0.10 Published 2010 Journal BMC Cardiovasc Disord Section Body Doc Link PMC2954875 Disease Relevance 0.75 Pain Relevance 0.16

General Comments

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