INT14971

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Context Info
Confidence 0.44
First Reported 1982
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 12
Total Number 13
Disease Relevance 11.35
Pain Relevance 1.48

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Afp) extracellular space (Afp) extracellular region (Afp)
molecular_function (Afp) cytoplasm (Afp)
Anatomy Link Frequency
Liver 2
spinal cord 1
Afp (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Analgesic 2 99.74 Very High Very High Very High
Spinal cord 8 99.32 Very High Very High Very High
imagery 16 98.96 Very High Very High Very High
Nicotine 2 96.52 Very High Very High Very High
abdominal pain 3 93.20 High High
tolerance 3 89.04 High High
Angina 1 87.20 High High
palliative 6 87.12 High High
Pain 1 80.88 Quite High
Paracetamol 4 76.36 Quite High
Disease Link Frequency Relevance Heat
Cancer 146 100.00 Very High Very High Very High
Death 11 99.68 Very High Very High Very High
Endodermal Sinus Tumor 6 99.52 Very High Very High Very High
Spinal Cord Compression 2 99.32 Very High Very High Very High
Liver Cancer 10 98.24 Very High Very High Very High
Hepatocellular Cancer 150 97.02 Very High Very High Very High
Metastasis 44 96.28 Very High Very High Very High
Recurrence 10 95.20 Very High Very High Very High
Splenomegaly 1 94.96 High High
Jaundice 3 94.12 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Immunohistochemically tumor cells were immunoreactive for AFP, alpha 1 antitrypsin, and carcinoembryonic antigens.
Regulation (immunoreactive) of AFP associated with cancer
1) Confidence 0.44 Published 2006 Journal Int. J. Gynecol. Cancer Section Abstract Doc Link 16803543 Disease Relevance 0.79 Pain Relevance 0.09
[Significant effects on alpha-fetoprotein (AFP) concentration in maternal serum in pregnancy].
Regulation (effects) of AFP associated with analgesic
2) Confidence 0.27 Published 1991 Journal Zentralbl Gynakol Section Title Doc Link 1711749 Disease Relevance 0.09 Pain Relevance 0.29
Starting on the day of peak ALT, AFP values were significantly higher in survivors than in nonsurvivors.
Regulation (values) of AFP
3) Confidence 0.23 Published 2005 Journal Hepatology Section Abstract Doc Link 15690478 Disease Relevance 0.36 Pain Relevance 0.29
All the values of serum alpha-fetoprotein (AFP) in the patients who exhibited pretreatment levels exceeding 100 ng/ml dropped by more than 50%, and in 55% of them it fell below 20 ng/ml.
Regulation (values) of serum alpha-fetoprotein
4) Confidence 0.22 Published 1987 Journal Cancer Section Abstract Doc Link 2441837 Disease Relevance 0.62 Pain Relevance 0
Regarding the changes of AFP value before and after treatment, no survivor over 6 months was encountered in the cases which revealed an increasing value of AFP.
Regulation (value) of AFP
5) Confidence 0.20 Published 1982 Journal Gan To Kagaku Ryoho Section Abstract Doc Link 6191700 Disease Relevance 0.48 Pain Relevance 0.09
Prognostic factors are Child-Pugh and Okuda status, number of TACE courses and of embolizations, changes of alpha-fetoprotein levels, and association with tamoxifen treatment.
Regulation (changes) of alpha-fetoprotein
6) Confidence 0.09 Published 1996 Journal Dig. Dis. Sci. Section Abstract Doc Link 9011438 Disease Relevance 0.89 Pain Relevance 0.13
Combined chemotherapy with CDDP, VP16, and PEP brought the AFP and LDH 1 values down to 10 ng/ml and 27%, respectively.
Regulation (values) of AFP
7) Confidence 0.06 Published 1989 Journal Nippon Kyobu Geka Gakkai Zasshi Section Abstract Doc Link 2475556 Disease Relevance 0.50 Pain Relevance 0.09
Diagnosis depends mainly on age, abdominal symptoms, size and consistency of the tumor, and tumor markers AFP and hCG.
Regulation (depends) of AFP associated with cancer
8) Confidence 0.06 Published 1995 Journal Gan To Kagaku Ryoho Section Abstract Doc Link 7661594 Disease Relevance 2.21 Pain Relevance 0.09
Serum AFP response was also evaluated in patients with a serum AFP level greater than normal before Cyberknife treatment.
Regulation (response) of AFP
9) Confidence 0.03 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2940809 Disease Relevance 0.95 Pain Relevance 0
Serum AFP response was assessed in the 22 evaluable patients with an increased AFP level at baseline (Table 2).
Regulation (response) of AFP
10) Confidence 0.03 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2940809 Disease Relevance 1.08 Pain Relevance 0
We report here a patient with asymptomatic advanced HCC, normal LFTs, and normal AFP values presenting with spinal cord compression.
Regulation (values) of AFP in spinal cord associated with spinal cord
11) Confidence 0.03 Published 2005 Journal Dig. Dis. Sci. Section Abstract Doc Link 15745089 Disease Relevance 1.44 Pain Relevance 0.18
The diagnosis of HCC was confirmed by histopathology or by computed tomography (CT), magnetic resonance imaging (MRI), and angiographic findings in addition to elevated values of alpha-fetoprotein (AFP) using the guidelines proposed by the Korea Liver Cancer Study Group (15).
Regulation (values) of AFP in Liver associated with liver cancer, hepatocellular cancer and imagery
12) Confidence 0.02 Published 2010 Journal Cancer Research and Treatment : Official Journal of Korean Cancer Association Section Body Doc Link PMC3021739 Disease Relevance 1.18 Pain Relevance 0.19
The diagnosis of HCC was confirmed by pathology in five patients; for the remaining 41 patients, the diagnosis was established by CT, MRI, and angiographic findings in addition to elevated values of AFP using the guidelines proposed by the Korea Liver Cancer Study Group (15).
Regulation (values) of AFP in Liver associated with liver cancer, hepatocellular cancer and imagery
13) Confidence 0.02 Published 2010 Journal Cancer Research and Treatment : Official Journal of Korean Cancer Association Section Body Doc Link PMC3021739 Disease Relevance 0.76 Pain Relevance 0.05

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