INT149743

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.54
Pain Relevance 1.50

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (P2rx2)
Anatomy Link Frequency
microglia 2
Ean5 (Rattus norvegicus)
P2rx2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuritis 10 100.00 Very High Very High Very High
allodynia 5 100.00 Very High Very High Very High
Neuropathic pain 5 97.24 Very High Very High Very High
withdrawal 1 87.64 High High
Dorsal horn 3 86.44 High High
Peripheral nerve injury 1 56.52 Quite High
central sensitization 1 43.72 Quite Low
Inflammation 1 34.72 Quite Low
Disease Link Frequency Relevance Heat
Neuropathic Pain 10 100.00 Very High Very High Very High
Experimental Autoimmune Neuritis 10 100.00 Very High Very High Very High
Neuropathy 1 96.44 Very High Very High Very High
Immunization 1 82.32 Quite High
Nervous System Injury 1 56.52 Quite High
Syndrome 3 41.12 Quite Low
Guillain-barre Syndrome 2 36.44 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Our data demonstrate that EAN induces mechanical allodynia and P2X(4)R expression in spinal microglia, suggesting that EAN is a good animal model for neuropathic pain in polyneuropathy and spinal microglia activation might participate in EAN-induced neuropathic pain.
EAN Positive_regulation (induces) of Gene_expression (expression) of P2X in microglia associated with neuropathy, allodynia, neuropathic pain and neuritis
1) Confidence 0.10 Published 2008 Journal Neuroscience Section Abstract Doc Link 18276080 Disease Relevance 1.54 Pain Relevance 1.50

General Comments

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