INT149753

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Context Info
Confidence 0.38
First Reported 2006
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 2.59
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (P2rx3)
Anatomy Link Frequency
neuronal 2
ganglia 2
P2rx3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 3 90.52 High High
trigeminal ganglion 75 87.84 High High
ischemia 4 86.48 High High
monoamine 2 73.16 Quite High
dorsal root ganglion 8 62.48 Quite High
agonist 16 58.88 Quite High
Nerve growth factor 1 55.12 Quite High
qutenza 30 47.88 Quite Low
Serotonin 7 44.40 Quite Low
imagery 12 33.96 Quite Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 10 99.00 Very High Very High Very High
Nociception 17 98.80 Very High Very High Very High
Heart Injuries 2 97.48 Very High Very High Very High
Heart Rate Under Development 4 93.56 High High
Ganglion Cysts 104 87.84 High High
Coronary Artery Disease 4 86.48 High High
Arrhythmia Under Development 4 80.00 Quite High
Injury 2 75.00 Quite High
Pain 23 5.00 Very Low Very Low Very Low
Headache 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
A-317491 reduced the expression of P2X3 mRNA and protein in the myocardial ischemic injury.
Negative_regulation (reduced) of Transcription (expression) of P2X3 associated with myocardial infarction
1) Confidence 0.38 Published 2008 Journal Auton Neurosci Section Abstract Doc Link 18276198 Disease Relevance 1.15 Pain Relevance 0.16
In rats treated with A-317491, the expression of P2X3 immunoreactivity and mRNA in nodose ganglia was reduced.
Negative_regulation (reduced) of Transcription (expression) of P2X3 in ganglia
2) Confidence 0.37 Published 2008 Journal Auton Neurosci Section Abstract Doc Link 18276198 Disease Relevance 1.12 Pain Relevance 0.12
For real time PCR, the relative mRNA expression of P2X3, P2X2 and TRPV1 in the different samples was normalized to the neuronal ?
Negative_regulation (relative) of Transcription (expression) of P2X3 in neuronal
3) Confidence 0.26 Published 2006 Journal Mol Pain Section Body Doc Link PMC1448213 Disease Relevance 0.32 Pain Relevance 0.25

General Comments

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