INT149842

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Context Info
Confidence 0.67
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 1.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (C19orf10)
Anatomy Link Frequency
brain 1
C19orf10 (Homo sapiens)
Pain Link Frequency Relevance Heat
Cannabinoid 3 99.20 Very High Very High Very High
chemokine 6 98.88 Very High Very High Very High
Central grey 5 98.40 Very High Very High Very High
Analgesic 4 97.44 Very High Very High Very High
antagonist 3 91.80 High High
antinociception 4 88.16 High High
Antinociceptive 1 83.76 Quite High
Pain 3 53.12 Quite High
agonist 1 42.52 Quite Low
Cannabinoid receptor 1 42.20 Quite Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 5 98.40 Very High Very High Very High
Age-related Macular Degeneration 1 90.52 High High
Pain 1 53.12 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study reports the first in vivo evidence of a functional interaction between chemokine and cannabinoid systems in the brain, showing that the activation of SDF-1alpha/CXCL12 receptors (CXCR4) in the PAG interferes with the analgesic effects of WIN 55212-2.
Positive_regulation (activation) of SDF in brain associated with chemokine, analgesic, cannabinoid and central grey
1) Confidence 0.67 Published 2008 Journal J. Pharmacol. Exp. Ther. Section Abstract Doc Link 18281594 Disease Relevance 0.47 Pain Relevance 1.03

General Comments

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