INT149890

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Context Info
Confidence 0.48
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 1.56
Pain Relevance 0.41

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cilium (Gli1) DNA binding (Gli1) cytoplasm (Gli1)
cytosol (Gli1) nucleus (Gli1) molecular_function (Gli1)
Anatomy Link Frequency
plasma 4
Gli1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 6 85.40 High High
fibrosis 6 61.48 Quite High
Chronic pancreatitis 2 49.28 Quite Low
Disease Link Frequency Relevance Heat
Primary Sclerosing Cholangitis 18 96.60 Very High Very High Very High
Fibrosis 6 61.48 Quite High
Injury 2 52.44 Quite High
Pancreatitis 2 49.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Unexpectedly, however, adenovirus-mediated Gli-1 overexpression blocked the Ihh enhancement of both MT1-MMP localization on the plasma membrane and PSC migration.
Positive_regulation (overexpression) of Gene_expression (overexpression) of Gli-1 in plasma associated with primary sclerosing cholangitis
1) Confidence 0.48 Published 2008 Journal J. Cell. Physiol. Section Abstract Doc Link 18286538 Disease Relevance 0.78 Pain Relevance 0.20
Unexpectedly, however, adenovirus-mediated Gli-1 overexpression blocked the Ihh enhancement of both MT1-MMP localization on the plasma membrane and PSC migration.
Positive_regulation (mediated) of Gene_expression (overexpression) of Gli-1 in plasma associated with primary sclerosing cholangitis
2) Confidence 0.48 Published 2008 Journal J. Cell. Physiol. Section Abstract Doc Link 18286538 Disease Relevance 0.78 Pain Relevance 0.21

General Comments

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