INT149899

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Title
Documents 1
Total Number 2
Disease Relevance 1.69
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ihh) peptidase activity (Mmp7) extracellular region (Mmp7)
proteinaceous extracellular matrix (Mmp7) embryo development (Ihh) molecular_function (Ihh)
Anatomy Link Frequency
plasma 2
Ihh (Rattus norvegicus)
Mmp7 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
metalloproteinase 6 100.00 Very High Very High Very High
Chronic pancreatitis 2 92.04 High High
fibrosis 6 87.00 High High
Disease Link Frequency Relevance Heat
Primary Sclerosing Cholangitis 18 97.20 Very High Very High Very High
Pancreatitis 2 92.04 High High
Injury 2 88.32 High High
Fibrosis 6 87.00 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Furthermore, Ihh increased the amount of membrane-type 1 matrix metalloproteinase (MT1-MMP) and altered its localization on the plasma membrane, which plays a stimulatory role in cellular migration.
Ihh Positive_regulation (increased) of metalloproteinase in plasma associated with metalloproteinase
1) Confidence 0.04 Published 2008 Journal J. Cell. Physiol. Section Abstract Doc Link 18286538 Disease Relevance 0.93 Pain Relevance 0.33
Indian hedgehog promotes the migration of rat activated pancreatic stellate cells by increasing membrane type-1 matrix metalloproteinase on the plasma membrane.
Indian hedgehog Positive_regulation (increasing) of metalloproteinase in plasma associated with metalloproteinase
2) Confidence 0.04 Published 2008 Journal J. Cell. Physiol. Section Title Doc Link 18286538 Disease Relevance 0.77 Pain Relevance 0.33

General Comments

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