INT14991

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.11
First Reported 1991
Last Reported 1991
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 4
Disease Relevance 1.65
Pain Relevance 1.92

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (SFTPA1, MPO) mitochondrion (MPO) oxidoreductase activity (MPO)
aging (MPO) extracellular region (SFTPA1) nucleus (MPO)
Anatomy Link Frequency
PMN 2
SFTPA1 (Homo sapiens)
MPO (Homo sapiens)
Pain Link Frequency Relevance Heat
substance P 32 100.00 Very High Very High Very High
Neuropeptide 8 99.04 Very High Very High Very High
Enkephalin 4 97.52 Very High Very High Very High
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 28 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SP induced MPO release in a dose-dependent manner at concentrations ranging from 1 approximately 10 x 10(-4) M.
SP Positive_regulation (induced) of Localization (release) of MPO associated with urological neuroanatomy and substance p
1) Confidence 0.11 Published 1991 Journal J. Antibiot. Section Abstract Doc Link 1712007 Disease Relevance 0.39 Pain Relevance 0.47
Pyrrolomycin derivatives with an N-methylated pyrrole ring showed, however, a selective inhibition of the SP-induced MPO release.
SP Positive_regulation (induced) of Localization (release) of MPO associated with urological neuroanatomy and substance p
2) Confidence 0.10 Published 1991 Journal J. Antibiot. Section Abstract Doc Link 1712007 Disease Relevance 0.51 Pain Relevance 0.47
Based on this, we searched for microbial inhibitors against SP-induced MPO release.
SP Positive_regulation (induced) of Localization (release) of MPO associated with urological neuroanatomy and substance p
3) Confidence 0.10 Published 1991 Journal J. Antibiot. Section Abstract Doc Link 1712007 Disease Relevance 0.44 Pain Relevance 0.53
In order to search for microbial modulators of the activity of neuropeptide, we established a screen based on substance P (SP)-induced myeloperoxidase (MPO) release from human polymorphonuclear leukocytes (PMN).
SP Positive_regulation (induced) of Localization (release) of MPO in PMN associated with neuropeptide, urological neuroanatomy and substance p
4) Confidence 0.10 Published 1991 Journal J. Antibiot. Section Abstract Doc Link 1712007 Disease Relevance 0.32 Pain Relevance 0.45

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox