INT149998

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 1.73
Pain Relevance 0.28

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell proliferation (Bcl2l1) cytosol (Bcl2l1) mitochondrion (Bcl2l1)
growth (Bcl2l1) cytoskeleton (Bcl2l1) intracellular (Bcl2l1)
Bcl2l1 (Mus musculus)
Pain Link Frequency Relevance Heat
Clonidine 3 82.84 Quite High
cerebral cortex 2 75.00 Quite High
Disease Link Frequency Relevance Heat
Apoptosis 11 100.00 Very High Very High Very High
Hypoxia 13 99.90 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We propose that during hypoxia the increased ratio of (pro-apoptotic Bad and Bax/anti-apoptotic Bcl-xl and Bcl-2) in all the three compartments, will lead to altered mitochondrial and nuclear membrane permeability as well as caspase-9 activation in the cytosolic compartment.
Positive_regulation (lead) of Positive_regulation (increased) of Bcl-xl associated with hypoxia and apoptosis
1) Confidence 0.05 Published 2008 Journal Neurochem. Res. Section Abstract Doc Link 18293086 Disease Relevance 1.73 Pain Relevance 0.28

General Comments

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