INT150029

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Context Info
Confidence 0.18
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Alox15) oxidoreductase activity (Alox15) nucleolus (Alox15)
nucleus (Alox15) cytoplasm (Alox15)
Alox15 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Potency 1 85.92 High High
Inflammation 4 48.84 Quite Low
fibrosis 1 35.80 Quite Low
Pain 1 34.72 Quite Low
rheumatoid arthritis 1 34.48 Quite Low
Disease Link Frequency Relevance Heat
INFLAMMATION 2 48.84 Quite Low
Cirrhosis 1 35.80 Quite Low
Cancer 1 35.04 Quite Low
Pain 1 34.72 Quite Low
Rheumatoid Arthritis 1 34.48 Quite Low
Increased Venous Pressure Under Development 1 33.60 Quite Low
Asthma 1 32.92 Quite Low
Disease 1 32.24 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Evaluation of 5-LOX metabolites-by LC/MS/MS and ELISA confirmed that both compounds selectively inhibited all products downstream of 5-hydroperoxy eicosatetraenoic acid (5-HPETE), including 5-oxo-6,8,11,14-eicosatetraenoic acid (5-oxoETE), without inhibition of 12-lipoxygenase (12-LOX), 15-lipoxygenase (15-LOX), or cyclooxygenase (COX) products.
Gene_expression (products) of 15-LOX
1) Confidence 0.18 Published 2008 Journal Eur. J. Pharmacol. Section Abstract Doc Link 18295198 Disease Relevance 0 Pain Relevance 0.04

General Comments

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