INT15003

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Context Info
Confidence 0.35
First Reported 1991
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 0.80
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (GFAP) extracellular matrix organization (GFAP) cytoplasm (GFAP)
Anatomy Link Frequency
apoptotic cells 1
astrocytes 1
GFAP (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 1 99.16 Very High Very High Very High
allodynia 19 50.00 Quite Low
dorsal root ganglion 2 50.00 Quite Low
Spinal cord 32 44.08 Quite Low
Enkephalin 1 25.00 Low Low
Peripheral nervous system 6 5.00 Very Low Very Low Very Low
Demyelination 6 5.00 Very Low Very Low Very Low
withdrawal 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Buprenorphine 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Injury 96 99.60 Very High Very High Very High
Cicatrix 52 98.96 Very High Very High Very High
Targeted Disruption 2 82.88 Quite High
Spinal Cord Injury 140 60.80 Quite High
Severe Combined Immunodeficiency 54 50.00 Quite Low
Neuropathic Pain 19 50.00 Quite Low
Cancer 17 50.00 Quite Low
Ganglion Cysts 2 50.00 Quite Low
Necrosis 1 50.00 Quite Low
Apoptosis 1 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Few SC121 immunopositive cells co-localized with GFAP suggesting rare astrocytic differentiation (Fig. 4P–T).
Localization (localized) of GFAP
1) Confidence 0.35 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923623 Disease Relevance 0 Pain Relevance 0
The few human-GFAP cells observed were primarily localized near the injury epicenter (Fig. 7B).
Localization (localized) of GFAP associated with injury
2) Confidence 0.33 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2923623 Disease Relevance 0.75 Pain Relevance 0
Using immunostaining for caspase 3, NeuN, and GFAP, localization of apoptotic cells was observed.
Localization (localization) of GFAP in apoptotic cells
3) Confidence 0.30 Published 2008 Journal Spine Section Body Doc Link 18469688 Disease Relevance 0.05 Pain Relevance 0
To determine whether cultured astrocytes express opioid gene mRNA, a method was developed for co-localizing a cell-type specific immunocytochemical marker for astrocytes, glial fibrillary acidic protein (GFAP), and proenkephalin mRNA in situ hybridization signal using high affinity cRNA probes.
Localization (localizing) of acidic protein in astrocytes associated with opioid
4) Confidence 0.03 Published 1991 Journal J. Neurosci. Methods Section Abstract Doc Link 1712058 Disease Relevance 0 Pain Relevance 0.10

General Comments

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