INT150067

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.23
Pain Relevance 0.69

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Cnr1, Oprd1) signal transducer activity (Cnr1, Oprd1) signal transduction (Cnr1)
aging (Cnr1) cytoplasm (Oprd1)
Anatomy Link Frequency
cerebellum 2
Cnr1 (Mus musculus)
Oprd1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 3 100.00 Very High Very High Very High
opioid receptor 2 100.00 Very High Very High Very High
agonist 2 99.76 Very High Very High Very High
Cannabinoid 8 99.60 Very High Very High Very High
cannabis 1 96.08 Very High Very High Very High
Opioid 1 95.24 Very High Very High Very High
Cannabinoid receptor 2 75.00 Quite High
MU agonist 1 71.12 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 4 97.88 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The goal of this study was to evaluate whether acute treatments by endogenous cannabinoid agonist, selective CB1 or CB2 receptor antagonists modulate the expression of mu- (MOR) and delta- (DOR) opioid receptor mRNA levels and functional activity in the cerebellum of transgenic mice deficient in the CB1 type of cannabis receptors.
CB1 Regulation (modulate) of Gene_expression (expression) of opioid receptor mRNA in cerebellum associated with targeted disruption, cannabis, antagonist, cannabinoid, agonist and opioid receptor
1) Confidence 0.01 Published 2007 Journal Acta. Biol. Hung. Section Abstract Doc Link 18297798 Disease Relevance 0.23 Pain Relevance 0.69

General Comments

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