INT150108

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Context Info
Confidence 0.35
First Reported 2004
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 2.09
Pain Relevance 0.83

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neuronal 2
Slc37a4 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 127 97.24 Very High Very High Very High
agonist 30 89.16 High High
Bile 9 85.16 High High
cytokine 9 74.92 Quite High
fibrosis 32 70.80 Quite High
Hippocampus 15 67.68 Quite High
Paracetamol 2 67.60 Quite High
imagery 10 5.00 Very Low Very Low Very Low
Inflammatory response 9 5.00 Very Low Very Low Very Low
tolerance 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Infection 87 100.00 Very High Very High Very High
Insulin Resistance 3 99.26 Very High Very High Very High
Alzheimer's Dementia 6 97.32 Very High Very High Very High
INFLAMMATION 137 97.24 Very High Very High Very High
Diabetes Mellitus 51 96.92 Very High Very High Very High
Disease 21 94.52 High High
Congenital Anomalies 49 91.48 High High
Cyst 60 83.28 Quite High
Targeted Disruption 6 75.68 Quite High
Injury 9 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hepatic messenger RNA (mRNA) levels of genes encoding enzymes involved in de novo G6P synthesis were unaltered, whereas glucose-6-phosphate hydrolase mRNA expressions were increased in TDGA-treated mice.
Positive_regulation (increased) of Gene_expression (expressions) of glucose-6-phosphate
1) Confidence 0.35 Published 2008 Journal Hepatology Section Abstract Doc Link 18302288 Disease Relevance 0 Pain Relevance 0.13
stimulates expression of the hepatobiliary phospholipid transporter Abcb4 [24, 62, 94, 144].

9.

Positive_regulation (stimulates) of Gene_expression (expression) of transporter
2) Confidence 0.02 Published 2010 Journal PPAR Research Section Body Doc Link PMC2948931 Disease Relevance 0 Pain Relevance 0.23
These findings are further substantiated by the enhanced L-FABP expression and a trend toward increased expression of the FA membrane transporter, FAT/CD36.
Positive_regulation (increased) of Gene_expression (expression) of transporter
3) Confidence 0.01 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864762 Disease Relevance 0.07 Pain Relevance 0.04
Full genome microarrays of brains reflected inflammation causing neuronal damage (Gfap), effects on host cell protein processing (ubiquitin ligase), synapse remodeling (Complement 1q), and also increased expression of PD-1L (a ligand that allows persistent LCMV brain infection) and CD 36 (a fatty acid translocase and oxidized LDL receptor that mediates innate immune response to beta amyloid which is associated with pro-inflammation in Alzheimer's disease).
Positive_regulation (increased) of Gene_expression (expression) of translocase in neuronal associated with inflammation, alzheimer's dementia, disease and infection
4) Confidence 0.01 Published 2008 Journal J Neuroinflammation Section Abstract Doc Link PMC2588578 Disease Relevance 1.60 Pain Relevance 0.43
The amelioration of insulin resistance by green tea is associated with the increased expression level of glucose transporter IV in a fructose-fed rat [3].
Positive_regulation (increased) of Gene_expression (expression) of transporter IV associated with insulin resistance
5) Confidence 0.01 Published 2004 Journal BMC Pharmacol Section Body Doc Link PMC517497 Disease Relevance 0.41 Pain Relevance 0

General Comments

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