INT150207

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Context Info
Confidence 0.34
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.06
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

structural molecule activity (NES) intracellular (NES) molecular_function (NES)
cytoplasm (NES)
Anatomy Link Frequency
stem cell 1
neural 1
NES (Homo sapiens)
Pain Link Frequency Relevance Heat
headache 1 80.20 Quite High
imagery 2 5.00 Very Low Very Low Very Low
Nerve growth factor 1 5.00 Very Low Very Low Very Low
dexamethasone 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Crohn's disease 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 1 98.68 Very High Very High Very High
Cancer 76 94.20 High High
Experimental Melanoma 2 93.44 High High
Ependymoma 4 89.68 High High
Glioma 24 84.84 Quite High
Glioblastoma 30 81.20 Quite High
Headache 1 80.20 Quite High
Neuroepithelial Neoplasms 1 78.48 Quite High
Anaplastic Astrocytoma 2 75.92 Quite High
Suicidal Behaviour 7 62.88 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The cells presented positive for GFAP, S-100 protein, vimentin, Nestin and neurofilament, and dotlike positive for epithelial membrane antigen, but negative for Syn and NeuN.
Positive_regulation (positive) of Nestin
1) Confidence 0.34 Published 2008 Journal Neuropathology Section Abstract Doc Link 18312548 Disease Relevance 0.77 Pain Relevance 0.08
These induced cells were found to be positive for neural markers such as Nestin, GFAP, NeuN, BT, Neurofilament (NF-70), and TH [Figures 9–11].


Positive_regulation (positive) of Nestin in neural
2) Confidence 0.19 Published 2010 Journal Asian Journal of Transfusion Science Section Body Doc Link PMC2847339 Disease Relevance 0.09 Pain Relevance 0
Spheroids from both sorted cell populations expressed the neural stem cell markers nestin and SOX2 and showed the ability to express the differentiation markers GFAP and ?
Positive_regulation (markers) of nestin in stem cell
3) Confidence 0.09 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2707627 Disease Relevance 1.20 Pain Relevance 0

General Comments

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