INT150253

Context Info Confidence 0.39 First Reported 2007 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0 Pain Relevance 0.15

growth (FOXP3) nucleus (FOXP3) intracellular (FOXP3) embryo development (FOXP3) protein complex (FOXP3) cytoplasm (FOXP3)

Anatomy Link Frequency oral mucosa 2 FOXP3 (Homo sapiens)

Pain Link Frequency Relevance Heat tolerance 8 86.68 abatacept 3 74.32 fibrosis 2 5.00 rheumatoid arthritis 2 5.00 cva 2 5.00 cytokine 1 5.00 withdrawal 1 5.00 Inflammation 1 5.00 Pain 1 5.00 agonist 1 5.00

Disease Link Frequency Relevance Heat Canker Sores 4 50.00 Apoptosis 1 33.88 Renal Disease 10 5.00 Death 8 5.00 Hypertension 5 5.00 Cytomegalovirus Infection 5 5.00 Infection 5 5.00 Diabetes Mellitus 4 5.00 Cancer 3 5.00 Renal Failure 3 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Moreover, levels of FOXP3 mRNA were significantly higher in the group with successful reversal of acute rejection than in the group without reversal.

Positive_regulation (higher) of Transcription (levels) of FOXP3

1) Confidence 0.39 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721321 Disease Relevance 0 Pain Relevance 0.15

We also attempted to detect the presence of FOXP3 and indoleamine 2,3-dioxygenase (IDO) mRNA in the lesional and non-lesional oral mucosa of RAS patients and healthy individuals using real-time PCR assay.

Positive_regulation (detect) of Transcription (presence) of FOXP3 in oral mucosa

2) Confidence 0.07 Published 2008 Journal J. Oral Pathol. Med. Section Body Doc Link 18318707 Disease Relevance 0 Pain Relevance 0

General Comments

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