INT150259

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.11
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nfkb2) signal transduction (Nfkb2) nucleus (Nfkb2)
extracellular matrix organization (Nfkb2) DNA binding (Nfkb2) cytoplasm (Nfkb2)
Nfkb2 (Mus musculus)
Pain Link Frequency Relevance Heat
COX2 2 10.00 Low Low
cINOD 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Colon Cancer 6 54.48 Quite High
Apoptosis 2 53.64 Quite High
INFLAMMATION 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NS-398 and DAPT inhibited cell proliferation and induced apoptosis in a dose time-dependent manner accompanied by significantly decreased Notch1 activity (P < 0.01), and resulted in a significant down-regulation of Hes1 and NF-kappaB2 (P < 0.01).
Regulation (regulation) of Negative_regulation (down) of NF-kappaB2
1) Confidence 0.02 Published 2008 Journal Dig. Dis. Sci. Section Body Doc Link 18320325 Disease Relevance 0.11 Pain Relevance 0

General Comments

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