INT150276

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Context Info
Confidence 0.37
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.34
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoskeleton (LRRFIP1) nucleus (LRRFIP1) DNA binding (LRRFIP1)
cytoplasm (LRRFIP1)
Anatomy Link Frequency
incisor 1
LRRFIP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 58 52.08 Quite High
Pain 5 50.00 Quite Low
metalloproteinase 5 50.00 Quite Low
substance P 4 50.00 Quite Low
cytokine 8 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Neuropeptide 4 5.00 Very Low Very Low Very Low
Inflammatory stimuli 4 5.00 Very Low Very Low Very Low
Neurotransmitter 2 5.00 Very Low Very Low Very Low
Glutamate receptor 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hemorrhage 6 99.52 Very High Very High Very High
Disorder Of Lipid Metabolism 6 98.70 Very High Very High Very High
Bacterial Respiratory Disease 6 90.44 High High
Pain 5 83.88 Quite High
Periodontal Pocket 2 67.12 Quite High
Mouth Disease 62 61.76 Quite High
INFLAMMATION 66 52.08 Quite High
Disease 10 51.04 Quite High
Adhesions 6 28.16 Quite Low
Periodontitis 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RESULTS: Painful stimulation of the upper central incisor caused significant elevations in GCF SP and MMP-8 levels of the stimulated tooth.
Positive_regulation (elevations) of GCF in incisor
1) Confidence 0.37 Published 2008 Journal Acta Odontol. Scand. Section Body Doc Link 18320414 Disease Relevance 0.08 Pain Relevance 0
On the other hand apolipoprotein B-100 falls into cluster B2vi, which follows the profile of the increase in GCF volume and bleeding index at test sites.
Positive_regulation (increase) of GCF associated with hemorrhage and disorder of lipid metabolism
2) Confidence 0.20 Published 2010 Journal Journal of Proteome Research Section Body Doc Link PMC2950674 Disease Relevance 0.68 Pain Relevance 0.03
At this time point, the GCF volume from test sites was already significantly increased above control sites.
Positive_regulation (increased) of GCF
3) Confidence 0.15 Published 2010 Journal Journal of Proteome Research Section Body Doc Link PMC2950674 Disease Relevance 0.57 Pain Relevance 0

General Comments

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