INT150290

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Context Info
Confidence 0.10
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.53
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Calca) extracellular region (Calca) nucleus (Calca)
intracellular (Calca) kinase activity (Grk1) cytoplasm (Calca)
Anatomy Link Frequency
neurons 2
Grk1 (Mus musculus)
Calca (Mus musculus)
Pain Link Frequency Relevance Heat
Calcitonin gene-related peptide 4 100.00 Very High Very High Very High
Root ganglion neuron 1 99.48 Very High Very High Very High
qutenza 2 90.84 High High
Disease Link Frequency Relevance Heat
Ganglion Cysts 1 99.28 Very High Very High Very High
Alopecia 6 95.56 Very High Very High Very High
Targeted Disruption 1 76.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RK, at concentrations higher than 1 microM, significantly increased CGRP release from dorsal root ganglion neurons (DRG) isolated from wild-type (WT) mice and this increase was completely reversed by capsazepine, an inhibitor of vanilloid receptor-1 activation.
RK Positive_regulation (increased) of Localization (release) of CGRP in neurons associated with ganglion cysts, root ganglion neuron and calcitonin gene-related peptide
1) Confidence 0.10 Published 2008 Journal Growth Horm. IGF Res. Section Abstract Doc Link 18321745 Disease Relevance 0.53 Pain Relevance 0.38

General Comments

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