INT150351

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 3.68
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (MMP12) signal transduction (EXT1) extracellular region (MMP12)
proteinaceous extracellular matrix (MMP12) transferase activity, transferring glycosyl groups (EXT1) Golgi apparatus (EXT1)
EXT1 (Homo sapiens)
MMP12 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 4 93.24 High High
Disease Link Frequency Relevance Heat
Multiple Hereditary Exostoses 10 100.00 Very High Very High Very High
Cancer 4 99.04 Very High Very High Very High
Malignant Neoplastic Disease 4 98.24 Very High Very High Very High
Congenital Anomalies 4 93.76 High High
Pain 4 93.24 High High
Osteochondroma 2 91.68 High High
Disease 6 90.52 High High
Enchondromatosis 14 86.48 High High
Exostoses 2 85.08 High High
Benign Tumor 2 83.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HME is a genetically heterogeneous disorder and is associated with mutations in EXT1 or EXT2 genes, which are both tumour suppressor genes.
EXT Binding (associated) of HME associated with cancer and multiple hereditary exostoses
1) Confidence 0.04 Published 2008 Journal Best Pract Res Clin Rheumatol Section Abstract Doc Link 18328980 Disease Relevance 1.85 Pain Relevance 0.14
HME is a genetically heterogeneous disorder and is associated with mutations in EXT1 or EXT2 genes, which are both tumour suppressor genes.
EXT1 Binding (associated) of HME associated with cancer and multiple hereditary exostoses
2) Confidence 0.02 Published 2008 Journal Best Pract Res Clin Rheumatol Section Abstract Doc Link 18328980 Disease Relevance 1.84 Pain Relevance 0.14

General Comments

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