INT15055

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Context Info
Confidence 0.42
First Reported 1983
Last Reported 1991
Negated 0
Speculated 1
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.24
Pain Relevance 0.67

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (Mme) plasma membrane (Mme)
Anatomy Link Frequency
lungs 2
Mme (Mus musculus)
Pain Link Frequency Relevance Heat
Pain threshold 2 99.60 Very High Very High Very High
substance P 1 97.32 Very High Very High Very High
qutenza 8 93.28 High High
Enkephalin 1 84.24 Quite High
Pain 2 63.20 Quite High
Analgesic 1 53.68 Quite High
analgesia 1 32.64 Quite Low
Disease Link Frequency Relevance Heat
Pain 3 99.60 Very High Very High Very High
Injury 1 43.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The effect of the inhibition of aminopeptidase and enkephalinase A on the pain threshold of mice and rats was investigated, using bestatin and thiorphan as selective peptidase inhibitors.
Spec (investigated) Regulation (effect) of Negative_regulation (inhibition) of enkephalinase associated with pain threshold
1) Confidence 0.42 Published 1983 Journal Neuropharmacology Section Abstract Doc Link 6363960 Disease Relevance 0.24 Pain Relevance 0.38
We studied the effects of neutral endopeptidase (NEP) and angiotensin-converting enzyme (ACE) inhibition on the airway responses and the recovery of endogenously released substance P- and neurokinin A-like immunoreactivities (SP-LI and NKA-LI) after tracheal injection of capsaicin in isolated guinea pig lungs superfused through the trachea.
Regulation (effects) of Negative_regulation (inhibition) of neutral endopeptidase in lungs associated with qutenza and substance p
2) Confidence 0.02 Published 1991 Journal J. Appl. Physiol. Section Abstract Doc Link 1713906 Disease Relevance 0 Pain Relevance 0.30

General Comments

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