INT15057

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Context Info
Confidence 0.09
First Reported 1986
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 0.97
Pain Relevance 2.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Mention Frequency
substantia nigra 1
nerve 1
medial 1
subthalamic nucleus 1
neurons 1
peroxidase (Caenorhabditis elegans)
Pain Term Frequency Confidence Heat
Spinal cord 7 99.52 Very High Very High Very High
Locus ceruleus 17 99.44 Very High Very High Very High
Ventral tegmentum 6 98.84 Very High Very High Very High
Thalamus 4 98.24 Very High Very High Very High
parabrachial 2 98.00 Very High Very High Very High
Substantia nigra 4 97.28 Very High Very High Very High
Central grey 15 96.16 Very High Very High Very High
qutenza 8 92.44 High High
substance P 2 89.80 High High
Glutamate 5 88.64 High High
Disease Term Frequency Confidence Heat
Urological Neuroanatomy 15 96.16 Very High Very High Very High
Pain 2 85.72 High High
Nociception 2 46.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Wheatgerm agglutinin conjugated to horseradish peroxidase (WGA:HRP) was injected into the cat hypoglossal nerve.
agglutinin Binding (conjugated) of peroxidase in nerve
1) Confidence 0.09 Published 1995 Journal Somatosens Mot Res Section Abstract Doc Link 8834297 Disease Relevance 0 Pain Relevance 0.24
The retrograde transport of horseradish peroxidase conjugated to wheatgerm agglutinin following injections in the ventral tegmental area of Tsai, medial substantia nigra and subthalamic nucleus was charted in relationship to the patterns of immunohistochemical staining in the forebrain following incubation of sections in antisera against substance P, neurotensin or leucine-enkephalin.
agglutinin Binding (conjugated) of peroxidase in subthalamic nucleus associated with ventral tegmentum, substantia nigra, enkephalin and substance p
2) Confidence 0.05 Published 1989 Journal Neuroscience Section Abstract Doc Link 2473414 Disease Relevance 0 Pain Relevance 0.23
Following injection of the retrograde tracer, wheatgerm agglutinin conjugated to horseradish peroxidase (WGA:HRP), into the ventroposterior medial thalamus (VPM), the number of neuronal profiles that were double-labeled with WGA:HRP and Glu-LI was greatest in principal sensory nucleus (Pr5), followed by subnuclei interpolaris (Sp5I) and caudalis (Sp5C).
agglutinin Binding (conjugated) of peroxidase in medial associated with thalamus
3) Confidence 0.03 Published 1987 Journal Somatosens Res Section Abstract Doc Link 2882592 Disease Relevance 0.07 Pain Relevance 0.47
When 60 days old, they were anesthetized and received 0.1-microliter thalamic injections of wheatgerm agglutinin conjugated to horseradish peroxidase (WGA:HRP) in the area of the central lateral nucleus (CL), the posterior group (PO), and the ventrobasal complex (VB), or the area of CL or VB.
agglutinin Binding (conjugated) of peroxidase in nucleus
4) Confidence 0.02 Published 1986 Journal Somatosens Res Section Abstract Doc Link 3809835 Disease Relevance 0 Pain Relevance 0.60
The retrograde transport of horseradish peroxidase conjugated to wheatgerm agglutinin following injections in the ventral tegmental area of Tsai, medial substantia nigra and subthalamic nucleus was charted in relationship to the patterns of immunohistochemical staining in the forebrain following incubation of sections in antisera against substance P, neurotensin or leucine-enkephalin.
agglutinin Binding (conjugated) of peroxidase in substantia nigra associated with ventral tegmentum, substantia nigra, enkephalin and substance p
5) Confidence 0.02 Published 1989 Journal Neuroscience Section Abstract Doc Link 2473414 Disease Relevance 0 Pain Relevance 0.23
Injections of the tracer wheatgerm agglutinin conjugated to horseradish peroxidase encompassing LC proper and the rostromedial pericoerulear area retrogradely labeled neurons in PAG located lateral and ventrolateral to the cerebral aqueduct; injections restricted to LC proper did not consistently label PAG neurons.
agglutinin Binding (conjugated) of peroxidase in neurons associated with locus ceruleus and central grey
6) Confidence 0.02 Published 1991 Journal J. Comp. Neurol. Section Abstract Doc Link 1713927 Disease Relevance 0.90 Pain Relevance 1.04

General Comments

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