INT150629

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 2.34
Pain Relevance 4.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
neurons 1
sympathetic 1
Ea1 (Mus musculus)
Pain Link Frequency Relevance Heat
electroacupuncture 160 100.00 Very High Very High Very High
Inflammation 28 98.58 Very High Very High Very High
antagonist 6 97.20 Very High Very High Very High
Antinociceptive 3 96.60 Very High Very High Very High
Thermal hyperalgesia 3 96.44 Very High Very High Very High
withdrawal 3 89.08 High High
Neuropeptide 2 54.28 Quite High
Central nervous system 1 48.76 Quite Low
Spinal cord 1 47.52 Quite Low
Osteoarthritis 1 13.44 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 19 98.58 Very High Very High Very High
Hyperalgesia 3 96.44 Very High Very High Very High
Urological Neuroanatomy 6 94.80 High High
Pressure And Volume Under Development 3 94.48 High High
Diabetes Mellitus 14 91.76 High High
Hyperglycemia 3 88.48 High High
Obesity 12 65.36 Quite High
Insulin Resistance 26 64.92 Quite High
Disease 3 16.24 Low Low
Knee Osteoarthritis 1 13.44 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Adrenalectomy significantly diminished HF EA-AI without affecting LF EA-AI.
Negative_regulation (diminished) of EA-AI associated with electroacupuncture
1) Confidence 0.15 Published 2008 Journal Brain Res. Bull. Section Abstract Doc Link 18355649 Disease Relevance 0.72 Pain Relevance 1.46
Low-frequency electroacupuncture suppresses carrageenan-induced paw inflammation in mice via sympathetic post-ganglionic neurons, while high-frequency EA suppression is mediated by the sympathoadrenal medullary axis.
Negative_regulation (suppression) of EA in neurons associated with inflammation and electroacupuncture
2) Confidence 0.15 Published 2008 Journal Brain Res. Bull. Section Title Doc Link 18355649 Disease Relevance 0.63 Pain Relevance 1.05
On the other hand, administration of 6-hydroxydopamine (a neurotoxin for peripheral sympathetic nerve endings) selectively blocked LF EA-AI.
Negative_regulation (blocked) of EA-AI in sympathetic associated with electroacupuncture
3) Confidence 0.15 Published 2008 Journal Brain Res. Bull. Section Abstract Doc Link 18355649 Disease Relevance 0.54 Pain Relevance 1.27
This supports the suggestion that the effect of EA in regulating BG may be insulin dependent.
Negative_regulation (effect) of EA associated with electroacupuncture
4) Confidence 0.04 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2964507 Disease Relevance 0.44 Pain Relevance 0.52

General Comments

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