INT150884

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Context Info
Confidence 0.47
First Reported 2006
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 3.12
Pain Relevance 2.19

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Il1a) extracellular space (Il1a) extracellular region (Il1a)
Anatomy Link Frequency
spinal cord 1
Il1a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 72 100.00 Very High Very High Very High
Eae 8 99.70 Very High Very High Very High
Spinal cord 16 99.68 Very High Very High Very High
Inflammation 109 98.68 Very High Very High Very High
nociceptor 1 96.72 Very High Very High Very High
Pain 12 95.24 Very High Very High Very High
Neuronal excitability 1 93.92 High High
Neuropathic pain 21 93.64 High High
Hyperalgesia 2 85.00 Quite High
allodynia 10 84.32 Quite High
Disease Link Frequency Relevance Heat
Injury 40 99.70 Very High Very High Very High
INFLAMMATION 109 98.68 Very High Very High Very High
Pain 10 95.24 Very High Very High Very High
Neuropathic Pain 33 93.64 High High
Apoptosis 9 88.64 High High
Hyperalgesia 2 85.00 Quite High
Nervous System Injury 16 77.72 Quite High
Nociception 2 70.24 Quite High
Body Weight 1 63.56 Quite High
Cognitive Disorder 13 56.24 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In naive and CCI-exposed rats, IL-1alpha mRNA and protein were not detected in the spinal cord.
Neg (not) Transcription (detected) of IL-1alpha in spinal cord associated with eae and spinal cord
1) Confidence 0.47 Published 2008 Journal Pain Section Abstract Doc Link 18374486 Disease Relevance 1.12 Pain Relevance 0.91
Four hours after injury, the rats were sacrificed and hippocampal IL-1?
Transcription (sacrificed) of IL-1 associated with injury
2) Confidence 0.17 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2930858 Disease Relevance 0.66 Pain Relevance 0
The mRNA expression of IL-1?
Transcription (expression) of IL-1
3) Confidence 0.06 Published 2010 Journal Radiat Oncol Section Body Doc Link PMC2845595 Disease Relevance 0.23 Pain Relevance 0.17
The mRNA expression of IL-1?
Transcription (expression) of IL-1
4) Confidence 0.06 Published 2010 Journal Radiat Oncol Section Body Doc Link PMC2845595 Disease Relevance 0.24 Pain Relevance 0.12
Evaluation of the effects of berberine chloride on the mRNA of IL-1?
Transcription (Evaluation) of IL-1
5) Confidence 0.04 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1693919 Disease Relevance 0.06 Pain Relevance 0.11
B, which regulates the transcription of proinflammatory cytokines, including IL-1, IL-6, and TNF?.
Transcription (transcription) of IL-1 associated with cytokine
6) Confidence 0.04 Published 2006 Journal BMC Neurosci Section Body Doc Link PMC1361774 Disease Relevance 0.80 Pain Relevance 0.87

General Comments

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