INT150938

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.80
Pain Relevance 1.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Nisch) endosome (Nisch) plasma membrane (Nisch)
cytoplasm (Nisch)
Nisch (Mus musculus)
Pain Link Frequency Relevance Heat
antagonist 10 100.00 Very High Very High Very High
Dopamine 4 100.00 Very High Very High Very High
antinociception 3 99.96 Very High Very High Very High
Serotonin 8 99.92 Very High Very High Very High
adenocard 6 99.30 Very High Very High Very High
Antinociceptive 2 96.48 Very High Very High Very High
imagery 6 63.36 Quite High
Pain 1 50.52 Quite High
Desipramine 1 23.52 Low Low
Nortriptyline 1 23.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 1 87.96 High High
Disease 56 86.08 High High
Cognitive Disorder 2 80.60 Quite High
Toxicity 4 26.84 Quite Low
Apoptosis 6 5.00 Very Low Very Low Very Low
Myelodysplastic Syndromes 4 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Congenital Anomalies 2 5.00 Very Low Very Low Very Low
Disorders Of Creatine Metabolism 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Caffeine and a selective adenosine A(2B) receptor antagonist but not imidazoline receptor antagonists modulate antinociception induced by diphenyl diselenide in mice.
Regulation (modulate) of imidazoline receptor associated with antinociception, adenocard and antagonist
1) Confidence 0.45 Published 2008 Journal Neurosci. Lett. Section Title Doc Link 18375062 Disease Relevance 0.09 Pain Relevance 0.87
Dimebon also had significant effect on Dopamine D1, D2S, D3 receptors, Imidazoline I2 receptor, Serotonin 5-HT2 and 5-HT2B receptors.
Regulation (effect) of Imidazoline I2 receptor associated with dopamine and serotonin
2) Confidence 0.01 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2577671 Disease Relevance 0.71 Pain Relevance 0.18

General Comments

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