INT150994

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.69
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Sfpq) aging (Il1b) DNA binding (Sfpq)
cytoplasm (Sfpq) extracellular space (Il1b) extracellular region (Il1b)
Anatomy Link Frequency
paw 2
Sfpq (Mus musculus)
Il1b (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 6 100.00 Very High Very High Very High
Inflammation 7 97.88 Very High Very High Very High
tail-flick 1 89.52 High High
Analgesic 4 75.00 Quite High
cOX1 1 25.00 Low Low
Disease Link Frequency Relevance Heat
INFLAMMATION 7 97.88 Very High Very High Very High
Pressure And Volume Under Development 2 78.08 Quite High
Disease 1 67.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
PSF could also markedly inhibit production of proinflammatory cytokines, especially IL-1 beta, IL-6 and TNF-alpha, but enhance production of anti-inflammatory cytokines of IL-4 and IL-10 in the carrageenan-injected paw tissues in rats.
PSF Negative_regulation (inhibit) of Gene_expression (production) of IL-1 beta in paw associated with inflammation and cytokine
1) Confidence 0.03 Published 2008 Journal Biol. Pharm. Bull. Section Abstract Doc Link 18379056 Disease Relevance 0.69 Pain Relevance 0.66

General Comments

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