From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.72
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.69
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Pten) mitochondrion (Pten) plasma membrane (Pten)
nucleus (Pten) intracellular (Pten) enzyme binding (Pten)
Anatomy Link Frequency
aortas 1
heart 1
Pten (Mus musculus)
Pain Link Frequency Relevance Heat
Clonidine 5 99.82 Very High Very High Very High
carbamazepine 1 5.00 Very Low Very Low Very Low
Substantia nigra 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
isoflurane 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
antagonist 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 18 99.92 Very High Very High Very High
Diabetes Mellitus 14 96.36 Very High Very High Very High
Dna Damage 1 95.76 Very High Very High Very High
Cancer 5 91.32 High High
Starvation 6 85.68 High High
Apoptosis 5 79.36 Quite High
Hypertrophy 15 61.28 Quite High
Tuberous Sclerosis 1 54.64 Quite High
Stress 5 52.64 Quite High
Alzheimer's Dementia 18 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further, even though complete knockout of PTEN in muscle led to a reduction in insulin-stimulated phosphorylation of PKB in the EDL and increased wet mass in the TA and heart, the response to overload was unaltered.
Phosphorylation (phosphorylation) of PTEN in heart associated with targeted disruption
1) Confidence 0.72 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2905373 Disease Relevance 0.16 Pain Relevance 0
The expression level of clonidine-induced phosphorylated PTEN (phosphatase and tensin homolog deleted on chromosome ten) was significantly increased in diabetic aortas, but chronic simvastatin did not affect it.
Phosphorylation (phosphorylated) of PTEN in aortas associated with diabetes mellitus and clonidine
2) Confidence 0.65 Published 2008 Journal J. Pharmacol. Sci. Section Abstract Doc Link 18391484 Disease Relevance 0.91 Pain Relevance 0.35
This can stimulate autophagy by activating AMPK or by upregulating phosphatase and tensin homologue (PTEN, a PIP3 3?
Phosphorylation (phosphatase) of PTEN
3) Confidence 0.16 Published 2010 Journal Seminars in Cell & Developmental Biology Section Body Doc Link PMC2938570 Disease Relevance 0.62 Pain Relevance 0

General Comments

This test has worked.

Personal tools