INT151174

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Context Info
Confidence 0.40
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 3
Total Number 3
Disease Relevance 0
Pain Relevance 1.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Grin2a) plasma membrane (Grin2a) locomotion (Grin2a)
Anatomy Link Frequency
prefrontal 3
striatum 1
Grin2a (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 17 100.00 Very High Very High Very High
nMDA receptor 16 100.00 Very High Very High Very High
long-term potentiation 74 97.28 Very High Very High Very High
Hippocampus 12 97.20 Very High Very High Very High
Morphine 24 97.08 Very High Very High Very High
amygdala 18 96.00 Very High Very High Very High
nMDA receptor antagonist 2 72.80 Quite High
Pyramidal cell 3 68.08 Quite High
Action potential 3 61.00 Quite High
imagery 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 47 50.00 Quite Low
Pain 1 5.00 Very Low Very Low Very Low
Shock 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Anaerobic Bacterial Infections 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the genetic section, the mRNA expression of NMDA receptor subunits (NR1 and NR2A) was measured in certain areas of the male rat brain (striatum, prefrontal cortex, hippocampus, hypothalamus and amygdala).
Negative_regulation (measured) of Transcription (expression) of NR2A in prefrontal associated with nmda receptor, hippocampus and amygdala
1) Confidence 0.40 Published 2008 Journal Pharmacology Section Abstract Doc Link 18391508 Disease Relevance 0 Pain Relevance 0.64
Bath application of the NR2A relatively selective antagonist NVP-AAM077 (0.3 ?
Negative_regulation (antagonist) of Transcription (application) of NR2A associated with antagonist
2) Confidence 0.35 Published 2008 Journal Mol Brain Section Body Doc Link PMC2570668 Disease Relevance 0 Pain Relevance 0.52
In the genetic section, the mRNA expression of NMDA receptor subunits (NR1 and NR2A) was measured in certain areas of the male rat brain (striatum, prefrontal cortex, hippocampus, hypothalamus and amygdala).
Negative_regulation (measured) of in striatum Transcription (expression) of NR2A in prefrontal associated with nmda receptor, hippocampus and amygdala
3) Confidence 0.14 Published 2008 Journal Pharmacology Section Abstract Doc Link 18391508 Disease Relevance 0 Pain Relevance 0.64

General Comments

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