INT1512
From wiki-pain
|
|
|
|
|
Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
In this work we have studied the binding of PRL in the male rat brain following morphine administration by both subcutaneous (s.c.) and intracerebroventricular (i.c.v.) injections. | |||||||||||||||
| |||||||||||||||
|
It was suggested that the down-regulation in PRL binding to some extent at least resulted from receptor overstimulation caused by the morphine-induced elevation in the concentrations of the endogenous hormone. | |||||||||||||||
| |||||||||||||||
|
In addition, these data provide evidence that a complex time-dependent binding of prolactin may occur in the plasma of the female rat liver. | |||||||||||||||
| |||||||||||||||
|
Effect of the association time of in vivo bound prolactin on the [125I]prolactin receptor assays of female rat livers. | |||||||||||||||
| |||||||||||||||
|
Role of prolactin-opiate interactions in the central regulation of pain threshold. | |||||||||||||||
| |||||||||||||||
|
It is suggested that the present findings may be of significance in the understanding of the interaction of the opioids, dopamine, and prolactin in the regulation of prolactin secretion. | |||||||||||||||
| |||||||||||||||
|
The decrease in prolactin binding was contrasted by elevated plasma levels of the hormone. | |||||||||||||||
| |||||||||||||||
|
The effect of chronically given morphine on the binding of ovine prolactin (oPRL) to specific areas in the male rat brain was studied. | |||||||||||||||
| |||||||||||||||
|
Modifications in prolactin specific binding in the rat liver induced by different non-steroidal anti-inflammatory drugs (indomethacin, piroxicam, ketoprofen, phenylbutazone, mefenamic acid and acetylsalicylic acid) have been studied. | |||||||||||||||
| |||||||||||||||
|
The degree of inhibitory activity on prolactin binding is related to the anti-inflammatory activity of each drug, which supports the hypothesis of an involvement of prostaglandin synthesis. | |||||||||||||||
| |||||||||||||||
|
An interaction between estrogen, progesterone and prolactin has been shown during the regression of the CL of the rat estrous cycle [34]. | |||||||||||||||
| |||||||||||||||
|
Elevated prolactin was not associated with sexual dysfunction among males in the overall population or among males treated with conventional antipsychotics. | |||||||||||||||
| |||||||||||||||
|
As prolactin was not associated with movement disorders, it is not likely a mediator for the relationship between movement and sexual functions. | |||||||||||||||
| |||||||||||||||
|
The associations between prolactin and estradiol, and between estradiol and sexual dysfunction, were not significant. | |||||||||||||||
| |||||||||||||||
|
Conventional antipsychotics and risperidone were included in the study due to their associations with elevated prolactin. | |||||||||||||||
| |||||||||||||||
|
CONCLUSION: DHEA-S was negatively associated, and prolactin positively associated with musculo-skeletal pain and psychological distress. | |||||||||||||||
| |||||||||||||||
|
Prolactin has been associated with many effects and has been implicated in the pathogenesis of pregnancy-related hypertensive disorders, although little is known about its vascular effects. | |||||||||||||||
| |||||||||||||||
|
Mating stimuli received by female rats activate a neuroendocrine mnemonic system which produces daily diurnal and nocturnal prolactin (PRL) surges for the first half of gestation, surges which help maintain corpora lutea function and a viable pregnancy. | |||||||||||||||
| |||||||||||||||
|
Mating stimuli received by female rats activate a neuroendocrine mnemonic system which produces daily diurnal and nocturnal prolactin (PRL) surges for the first half of gestation, surges which help maintain corpora lutea function and a viable pregnancy. | |||||||||||||||
| |||||||||||||||
|
We found that: the reduction in serotoninergic activity after PCPA administration did not modify serum PRL concentrations; the stimulatory effect of 5-HTP on PRL secretion was not observed before day 16; the effects of 5-HTP or 5-HTP and fluoxetine were similar in intact and orchidectomized males; a significant increase in PRL secretion took place after 8-OH-DPAT administration; the duration of the stimulatory effect of 5-HTP increased after alpha-diol treatment; and pituitary PRL content increased after 5-HTP injection in intact males and decreased in castrated males treated with testosterone or alpha-diol. | |||||||||||||||
| |||||||||||||||
|
General Comments
This test has worked.