INT151220

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (SIGMAR1, Prkca) nucleus (SIGMAR1, Prkca) plasma membrane (SIGMAR1, Prkca)
mitochondrion (Prkca) transport (SIGMAR1) nuclear envelope (SIGMAR1)
SIGMAR1 (Homo sapiens)
Prkca (Mus musculus)
Pain Link Frequency Relevance Heat
Immobilon 7 100.00 Very High Very High Very High
agonist 11 98.80 Very High Very High Very High
opioid receptor 5 86.36 High High
Enkephalin 1 25.00 Low Low
Disease Link Frequency Relevance Heat
Neuroblastoma 3 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In conclusion, hDOP-R desensitization upon etorphine exposure relies on the GRK2, PKC and tyrosine kinases while DPDPE and deltorphin I mediate desensitization at least via tyrosine kinases.
Negative_regulation (desensitization) of hDOP-R Negative_regulation (relies) of Positive_regulation (mediate) of PKC associated with immobilon
1) Confidence 0.00 Published 2008 Journal Cell. Signal. Section Abstract Doc Link 18395423 Disease Relevance 0.13 Pain Relevance 0.51

General Comments

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