INT151336

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Context Info
Confidence 0.30
First Reported 2008
Last Reported 2008
Negated 1
Speculated 1
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.20
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

oxidoreductase activity (Dio1) endoplasmic reticulum (Dio1)
Anatomy Link Frequency
lateral 2
Dio1 (Mus musculus)
Pain Link Frequency Relevance Heat
Dopamine 79 99.98 Very High Very High Very High
antagonist 28 96.68 Very High Very High Very High
agonist 29 89.60 High High
Serotonin 1 87.72 High High
Nucleus accumbens 2 84.80 Quite High
addiction 5 80.32 Quite High
GABAergic 14 78.00 Quite High
projection neuron 1 77.20 Quite High
Neurotransmitter 24 75.00 Quite High
Ventral tegmentum 1 70.56 Quite High
Disease Link Frequency Relevance Heat
Targeted Disruption 5 78.00 Quite High
Drug Dependence 1 50.72 Quite High
Ganglion Cysts 26 5.00 Very Low Very Low Very Low
Myopia 1 5.00 Very Low Very Low Very Low
Dislocations 1 5.00 Very Low Very Low Very Low
Refractive Errors 1 5.00 Very Low Very Low Very Low
Retina Disease 1 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low
Ocular Hypertension 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Except for a slight increase in the lateral septum, D1 receptor binding did not differ from wild-type in twenty-one other neocortical, limbic or basal ganglia regions examined in the KO.
Neg (not) Regulation (differ) of D1 Binding (binding) of in lateral
1) Confidence 0.30 Published 2008 Journal J. Chem. Neuroanat. Section Abstract Doc Link 18406571 Disease Relevance 0.20 Pain Relevance 0.58
To determine whether dopamine acting through D1 receptors mediates light resetting of retinal PER2::LUC rhythms, we applied the D1 receptor antagonist SCH-23390 (50 ?
Spec (whether) Regulation (acting) of D1 Binding (receptors) of associated with dopamine and antagonist
2) Confidence 0.14 Published 2008 Journal PLoS Biology Section Body Doc Link PMC2567003 Disease Relevance 0 Pain Relevance 0.31

General Comments

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