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Context Info
Confidence 0.00
First Reported 2005
Last Reported 2005
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.46

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ptpn6) phosphatase activity (Ptpn6) cell proliferation (Ptpn6)
nucleus (Ptpn6) cytoplasm (Ptpn6)
Anatomy Link Frequency
brain 2
Ptpn6 (Mus musculus)
Pain Link Frequency Relevance Heat
Enkephalin 2 99.60 Very High Very High Very High
Intracerebroventricular 1 97.04 Very High Very High Very High
opioid receptor 2 96.32 Very High Very High Very High
Antinociceptive 1 95.68 Very High Very High Very High
Kappa opioid receptor 1 92.84 High High
Delta opioid receptors 1 64.00 Quite High


Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The compound (100 microM) significantly decreased the specific binding of [3H]D-Ala2, N-Me-Phe4, Gly5-ol-enkephalin (DAMGO) and [3H]D-Pen2, D-Pen5-enkephalin (DPDPE) at the mu- and delta-opioid receptor, respectively, but has no effect on the binding of [3H]U-69,593 at the kappa-opioid receptor of rat brain slices.
Negative_regulation (decreased) of N-Me-Phe4 Binding (binding) of in brain associated with kappa opioid receptor, opioid receptor and enkephalin
1) Confidence 0.00 Published 2005 Journal Res. Commun. Mol. Pathol. Pharmacol. Section Abstract Doc Link 18426082 Disease Relevance 0 Pain Relevance 0.46

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