INT151522

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Context Info
Confidence 0.37
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 4.28
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

methyltransferase activity (NSD1) chromosome (NSD1) nucleus (NSD1)
Anatomy Link Frequency
STO 1
NSD1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 1 91.76 High High
anesthesia 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Weight Loss 1 100.00 Very High Very High Very High
Fatigue 1 98.72 Very High Very High Very High
Recurrence 4 96.80 Very High Very High Very High
Sotos Syndrome 54 93.68 High High
Dysphagia 1 92.64 High High
Pain 1 91.76 High High
Acromegaly 2 81.08 Quite High
Stomach Cancer 1 80.76 Quite High
Homocystinuria 2 80.60 Quite High
Marfan Syndrome 2 79.96 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It has been suggested that this lack of family cases is associated with an underlying defect in fertility associated with NSD1 mutations.
NSD1 Binding (associated) of
1) Confidence 0.37 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC2018686 Disease Relevance 1.82 Pain Relevance 0
Chromosome analysis of both parent needs to be performed when a deletion of NSD1 is detected in the affected child.
NSD1 Binding (deletion) of
2) Confidence 0.37 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC2018686 Disease Relevance 1.76 Pain Relevance 0
Fatigue, the financial impact and specific emotional problems such as "thinking about their illness" (STO-ANX) and "worry about weight loss or future health" (STO-BI) were persistently bothersome for some patients.
STO Binding (thinking) of in STO associated with weight loss and fatigue
3) Confidence 0.36 Published 2008 Journal Med. Oncol. Section Abstract Doc Link 18431552 Disease Relevance 0.69 Pain Relevance 0.09

General Comments

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