INT151527

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Context Info
Confidence 0.40
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 3.76
Pain Relevance 0.35

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Olfr148) plasma membrane (Olfr148) signal transducer activity (Olfr148)
Anatomy Link Frequency
apoptotic cell 1
Olfr148 (Mus musculus)
Pain Link Frequency Relevance Heat
Etanercept 26 98.84 Very High Very High Very High
fibrosis 1 93.68 High High
Paracetamol 2 75.00 Quite High
Potency 52 50.00 Quite Low
Inflammation 8 28.52 Quite Low
cytokine 9 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
rheumatoid arthritis 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Diabetic Retinopathy 22 99.80 Very High Very High Very High
Diabetes Mellitus 71 99.12 Very High Very High Very High
Death 37 98.92 Very High Very High Very High
Apoptosis 113 96.56 Very High Very High Very High
Cirrhosis 1 93.68 High High
End Stage Liver Disease 2 92.64 High High
Necrosis 8 85.40 High High
Injury 11 82.76 Quite High
Acute Liver Failure 3 75.00 Quite High
Poisoning 2 75.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This time, no movement in M30 levels was seen until the M30 levels rapidly increased indicating the inevitable death of the patient, while LFTs did not change.
Positive_regulation (increased) of M30 associated with death
1) Confidence 0.40 Published 2008 Journal Liver Int. Section Abstract Doc Link 18433398 Disease Relevance 1.51 Pain Relevance 0.19
Animals treated with LNA ASOs 1b, 4b or 5b all showed greatly increased M30 staining relative to saline treated animals (Figure 5), providing further evidence for apoptosis induced by treatment with the LNA ASOs.
Positive_regulation (increased) of M30 associated with apoptosis
2) Confidence 0.17 Published 2007 Journal Nucleic Acids Research Section Body Doc Link PMC1802611 Disease Relevance 0.78 Pain Relevance 0
IHC revealed increased immunoreactivity for M30 within the trophoblast following H/R.
Positive_regulation (increased) of M30
3) Confidence 0.14 Published 2007 Journal Placenta Section Body Doc Link PMC1895600 Disease Relevance 0.34 Pain Relevance 0
The increase in M30 staining observed in diabetic retinas suggested the involvement of caspases in mediating apoptotic cell death.
Positive_regulation (increase) of M30 in apoptotic cell associated with diabetes mellitus, apoptosis and death
4) Confidence 0.06 Published 2009 Journal Molecular Vision Section Body Doc Link PMC2716944 Disease Relevance 1.13 Pain Relevance 0.16

General Comments

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