INT151567

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Context Info
Confidence 0.72
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 3.63
Pain Relevance 1.26

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (Tlr9) endoplasmic reticulum (Tlr9) plasma membrane (Tlr9)
cellular_component (Tlr9) lysosome (Tlr9) cytoplasm (Tlr9)
Anatomy Link Frequency
proximal 2
whiskers 1
Tlr9 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuritis 10 100.00 Very High Very High Very High
Inflammation 56 92.88 High High
Demyelination 2 92.20 High High
Peripheral nervous system 2 91.36 High High
Central nervous system 2 90.68 High High
nud 12 79.72 Quite High
Angina 4 50.00 Quite Low
Inflammatory mediators 2 48.84 Quite Low
cytokine 42 40.60 Quite Low
spastic colon 68 26.56 Quite Low
Disease Link Frequency Relevance Heat
Experimental Autoimmune Neuritis 10 100.00 Very High Very High Very High
Cold Sores 122 99.24 Very High Very High Very High
Syndrome 4 93.92 High High
Sprains And Strains 118 93.24 High High
INFLAMMATION 62 92.88 High High
Demyelinating Disease 2 92.20 High High
Stable Angina Pectoris 4 88.44 High High
Acute Coronary Syndrome 4 88.12 High High
Genetic Predisposition To Disease 32 83.16 Quite High
Dyspepsia 12 79.72 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Expression of endosomal Tlr9 was elevated in the whiskers area of the DA rats at 1 dpi and in PVG from 2 dpi.
Gene_expression (Expression) of Tlr9 in whiskers
1) Confidence 0.72 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929186 Disease Relevance 0.09 Pain Relevance 0
Interestingly, Tlr9 expression has also been associated with phagocytic capacity [13] and the increase in mRNA seen in PVG correlates with the increased infiltration of phagocytic cells seen in this strain compared to DA.
Gene_expression (expression) of Tlr9 associated with sprains and strains
2) Confidence 0.72 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2929186 Disease Relevance 0.59 Pain Relevance 0.05
Expression of TLR4 and TLR9 mRNA in Lewis rats with experimental allergic neuritis.
Gene_expression (Expression) of TLR9 associated with experimental autoimmune neuritis and neuritis
3) Confidence 0.65 Published 2007 Journal Neuroimmunomodulation Section Title Doc Link 18434754 Disease Relevance 0.66 Pain Relevance 0.59
In this study, we observed the expression of mRNA of TLR4 and TLR9 in EAN rats.
Gene_expression (expression) of TLR9 associated with neuritis
4) Confidence 0.65 Published 2007 Journal Neuroimmunomodulation Section Abstract Doc Link 18434754 Disease Relevance 0.67 Pain Relevance 0.55
0.0203) (Figure 4a & 4b), TLR8 in the proximal (p<0.0001) and the distal colonic mucosa (p<0.0001) (Figure 4c & 4d), TLR9 in the proximal (p?
Gene_expression (0.0203) of TLR9 in proximal
5) Confidence 0.47 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2785428 Disease Relevance 0.73 Pain Relevance 0.04
0.0203) (Figure 4a & 4b), TLR8 in the proximal (p<0.0001) and the distal colonic mucosa (p<0.0001) (Figure 4c & 4d), TLR9 in the proximal (p?
Gene_expression (proximal) of TLR9 in proximal
6) Confidence 0.47 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2785428 Disease Relevance 0.72 Pain Relevance 0.04
TLR9 expression levels were not significantly different among the 3 groups.
Gene_expression (expression) of TLR9
7) Confidence 0.15 Published 2009 Journal Circ. J. Section Body Doc Link 19556696 Disease Relevance 0.18 Pain Relevance 0

General Comments

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