INT151661

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Context Info
Confidence 0.39
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Abstract
Documents 1
Total Number 2
Disease Relevance 0.13
Pain Relevance 0.66

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (gr)
gr (Mus musculus)
Pain Link Frequency Relevance Heat
antidepressant 8 99.52 Very High Very High Very High
tricyclic antidepressant 2 96.80 Very High Very High Very High
depression 2 85.04 High High
fluoxetine 2 81.60 Quite High
Desipramine 2 81.12 Quite High
Disease Link Frequency Relevance Heat
Cancer 2 73.20 Quite High
Depression 2 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
No effect of selective inhibitors of p38-MAPK, phosphatidylinositol 3-kinase (PI3-K)/Akt, and glycogen synthase kinase (GSK-3) on the imipramine-induced inhibition of GR function was detected.
Neg (No) Regulation (effect) of Negative_regulation (inhibition) of GR
1) Confidence 0.39 Published 2008 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 18441395 Disease Relevance 0.07 Pain Relevance 0.35
Moreover, it was found that JNK- and ERK-MAPK were oppositely involved in the regulation of the imipramine-induced inhibition of the GR functional activity.
Regulation (regulation) of Negative_regulation (inhibition) of GR
2) Confidence 0.39 Published 2008 Journal J. Physiol. Pharmacol. Section Abstract Doc Link 18441395 Disease Relevance 0.06 Pain Relevance 0.31

General Comments

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