INT151682

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Context Info
Confidence 0.24
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 1.98
Pain Relevance 0.88

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (STON1)
Anatomy Link Frequency
STN 1
STON1 (Homo sapiens)
Pain Link Frequency Relevance Heat
deep brain stimulation 145 100.00 Very High Very High Very High
palliative 4 86.72 High High
Thalamus 64 75.48 Quite High
Thalamotomy 10 69.52 Quite High
imagery 5 50.00 Quite Low
cva 3 46.16 Quite Low
Multiple sclerosis 1 34.40 Quite Low
Neurotransmitter 6 14.20 Low Low
Dopamine 37 13.52 Low Low
headache 1 10.00 Low Low
Disease Link Frequency Relevance Heat
Cognitive Disorder 17 97.48 Very High Very High Very High
Hypokinesia 13 96.44 Very High Very High Very High
Parkinson's Disease 75 93.88 High High
Disease 244 92.68 High High
Tremor 35 91.52 High High
Gliosis 1 77.84 Quite High
Dyskinesias 41 67.68 Quite High
Aging 2 63.36 Quite High
Dysphagia 2 59.08 Quite High
Dysarthria 3 58.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The age-related positional change of the STN should be considered in target determination for deep brain stimulation procedures.


Regulation (change) of STN in STN
1) Confidence 0.24 Published 2008 Journal Neuroradiology Section Body Doc Link 18443775 Disease Relevance 0 Pain Relevance 0
Indeed, maintaining the flexibility to perform model-based control the STN, GPi or VIM, depending upon a patientÂ’s symptom complex, is a challenge for future work.
Regulation (control) of STN
2) Confidence 0.13 Published 2010 Journal Philosophical transactions. Series A, Mathematical, physical, and engineering sciences Section Body Doc Link PMC2944387 Disease Relevance 0.32 Pain Relevance 0.05
Although the STN is now the dominant DBS target, it is unclear whether the GPi, with a less burdensome set of cognitive side effects, might be better for some patients (Anderson et al. 2005).
Regulation (target) of STN associated with cognitive disorder and deep brain stimulation
3) Confidence 0.07 Published 2010 Journal Philosophical transactions. Series A, Mathematical, physical, and engineering sciences Section Body Doc Link PMC2944387 Disease Relevance 0.83 Pain Relevance 0.38
The relative safety and efficacy of STN vs GPi DBS, however, has been compared formerly in only small studies (Burchiel et al 1999).
Regulation (efficacy) of STN associated with deep brain stimulation
4) Confidence 0.01 Published 2008 Journal Neuropsychiatric Disease and Treatment Section Body Doc Link PMC2536542 Disease Relevance 0.83 Pain Relevance 0.46

General Comments

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