INT151741

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Context Info
Confidence 0.44
First Reported 2009
Last Reported 2010
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.78
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PDGFRA) nucleus (PDGFRA) extracellular matrix organization (PDGFRA)
cytoplasm (PDGFRA)
PDGFRA (Homo sapiens)
Pain Link Frequency Relevance Heat
Snapping jaw 1 87.92 High High
abdominal pain 2 68.00 Quite High
cva 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Temporomandibular Joint Syndrome 1 87.92 High High
Cancer 51 83.32 Quite High
Malignant Neoplastic Disease 3 80.68 Quite High
Abdominal Pain 2 68.00 Quite High
Hemorrhage 4 67.24 Quite High
Metastasis 3 61.44 Quite High
Gastrointestinal Stromal Tumor 35 56.52 Quite High
Recurrence 29 50.00 Quite Low
Necrosis 9 24.64 Low Low
Emergencies 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Imatinib, a tyrosine kinase (TKI) inhibitor, antagonizes the effects of the KIT and PDGFRA proteins and has revolutionized the treatment of advanced and unresectable GISTs [5].
Regulation (effects) of PDGFRA
1) Confidence 0.44 Published 2010 Journal World J Surg Oncol Section Body Doc Link PMC2965163 Disease Relevance 0.69 Pain Relevance 0.07
Changes in surface markers (CD105, CD44, SSEA, PDGFR alpha) after the differentiation treatments were also analyzed.
Regulation (Changes) of PDGFR alpha
2) Confidence 0.06 Published 2009 Journal Stem Cells Dev. Section Abstract Doc Link 18454697 Disease Relevance 0.09 Pain Relevance 0.09

General Comments

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