INT151758

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Context Info
Confidence 0.63
First Reported 2006
Last Reported 2010
Negated 6
Speculated 2
Reported most in Body
Documents 91
Total Number 93
Disease Relevance 14.54
Pain Relevance 24.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PYCARD) signal transduction (PYCARD) intracellular (PYCARD)
cytoplasm (PYCARD)
Anatomy Link Frequency
PPC 4
brain 2
spleen 2
row 2
parietal 2
PYCARD (Homo sapiens)
Pain Link Frequency Relevance Heat
Transcranial magnetic stimulation 8672 100.00 Very High Very High Very High
depression 208 99.96 Very High Very High Very High
imagery 212 99.80 Very High Very High Very High
nerve block 395 99.76 Very High Very High Very High
Analgesic 2 99.62 Very High Very High Very High
positron emission tomography 88 99.48 Very High Very High Very High
Somatosensory cortex 148 99.28 Very High Very High Very High
Neuropathic pain 3 99.28 Very High Very High Very High
Migraine 25 98.92 Very High Very High Very High
Neurobehavioral 32 98.68 Very High Very High Very High
Disease Link Frequency Relevance Heat
Apoptosis 13 100.00 Very High Very High Very High
Depression 251 99.96 Very High Very High Very High
Convulsion 76 99.96 Very High Very High Very High
Disease 276 99.64 Very High Very High Very High
Neuropathic Pain 3 99.28 Very High Very High Very High
Migraine With Aura 2 98.92 Very High Very High Very High
Sleep Disorders 3 98.56 Very High Very High Very High
Cognitive Disorder 278 98.32 Very High Very High Very High
Irritable Bowel Syndrome /

Irritable Bowel Syndrome Super / Visceral Pain

2 97.92 Very High Very High Very High
Cancer 93 97.80 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In sum, exactly the same TMS that had produced (ipsilateral) enhancement of somatosensory median-nerve detection in Experiment 1 now produced reliable impairment of somatosensory median-nerve intensity-discrimination instead (now regardless of the side of somatosensory stimulation, see Section 5).
Gene_expression (produced) of TMS in nerve associated with transcranial magnetic stimulation
1) Confidence 0.63 Published 2010 Journal Neuropsychologia Section Body Doc Link PMC2956832 Disease Relevance 0 Pain Relevance 0.32
Overall, TMS has proved to be relatively safe with a few cases of seizures associated primarily with repetitive stimulation at higher frequencies (i.e., 10?
Gene_expression (safe) of TMS associated with convulsion and transcranial magnetic stimulation
2) Confidence 0.58 Published 2010 Journal Frontiers in Systems Neuroscience Section Body Doc Link PMC2950743 Disease Relevance 0.17 Pain Relevance 0.26
Studies using TMS and imaging in separate sessions
Gene_expression (using) of TMS associated with transcranial magnetic stimulation and imagery
3) Confidence 0.58 Published 2010 Journal Frontiers in Systems Neuroscience Section Body Doc Link PMC2950743 Disease Relevance 0.08 Pain Relevance 0.57
Overall, TMS has proved to be relatively safe with a few cases of seizures associated primarily with repetitive stimulation at higher frequencies (i.e., 10?
Gene_expression (proved) of TMS associated with convulsion and transcranial magnetic stimulation
4) Confidence 0.58 Published 2010 Journal Frontiers in Systems Neuroscience Section Body Doc Link PMC2950743 Disease Relevance 0.17 Pain Relevance 0.25
The nature of the effect depended on the similarity of the test stimulus to that presented during rTMS, suggesting that the effects of rTMS depend specifically on the level of activation of a given subpopulation of neurons.
Gene_expression (presented) of rTMS in neurons
5) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2860988 Disease Relevance 0 Pain Relevance 0.04
These results (Figure 2) represent the average performance over a 10-minute, post-rTMS period during which the test stimulus was shown repeatedly at a single retinal location.
Gene_expression (period) of rTMS
6) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2860988 Disease Relevance 0 Pain Relevance 0.04
This spatial suppression can be inhibited using offline 1 Hz rTMS of MT/V5, leading to improved motion discrimination of large (8 degree) stimuli [47].
Gene_expression (using) of rTMS
7) Confidence 0.58 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2860988 Disease Relevance 0.06 Pain Relevance 0.03
Third, generally; how do TMS effects and fMRI connectivity relate?
Gene_expression (effects) of TMS associated with transcranial magnetic stimulation
8) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.41
Importantly, this TMS-induced right fronto-parietal network effect was only found during TMS over right, but not left, PPC and only during active visuospatial judgment.
Gene_expression (found) of TMS-induced in PPC associated with transcranial magnetic stimulation
9) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0.09 Pain Relevance 0.43
It is because of this general trend that the most sensitive and controlled measure of TMS effect in this study was a difference in RT between ANGLE-trials and COLOR-trials (RTdif).
Gene_expression (effect) of TMS associated with transcranial magnetic stimulation
10) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.23
And fourth, specifically; how do the causality and information flow analyses of fMRI EC and TMS chronometry relate?
Gene_expression (chronometry) of TMS associated with transcranial magnetic stimulation
11) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.38
Third, and perhaps most important: to directly address the issue of potential differences in TMS effects between PPC and MFG, we statistically analyzed the differences between the two stimulation sites per time window using paired samples t-tests (two-tailed).
Gene_expression (effects) of TMS associated with transcranial magnetic stimulation
12) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.36
Overall, it seems that both TMS over PPC and TMS over MFG had an effect on task-specific reaction times, as measured by RTdif scores.
Gene_expression (over) of TMS associated with transcranial magnetic stimulation
13) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.19
Overall, it seems that both TMS over PPC and TMS over MFG had an effect on task-specific reaction times, as measured by RTdif scores.
Gene_expression (over) of TMS associated with transcranial magnetic stimulation
14) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.19
PPC information flow occurs in between 267 and 367 ms, and the apparent contradiction between fMRI EC and TMS chronometry was due to our design, or 2) TMS chronometry and fMRI EC measured different aspects of brain function, which means that they were complementary rather than competitive; the first option is implausible and the second remains.
Gene_expression (chronometry) of TMS in brain associated with transcranial magnetic stimulation
15) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.26
We thus analyzed TW1, TW2, TW3, TW4 as experimental conditions of interest, one time control condition (TC), and SHAM TMS as a sham control condition (SC).
Spec (analyzed) Gene_expression (analyzed) of SHAM TMS associated with transcranial magnetic stimulation
16) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.38
Importantly, this TMS-induced right fronto-parietal network effect was only found during TMS over right, but not left, PPC and only during active visuospatial judgment.
Gene_expression (found) of TMS in PPC associated with transcranial magnetic stimulation
17) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0.09 Pain Relevance 0.40
Initially another time window was tested, but since participants in this condition responded early around half of the time, we left this ambiguous time window out of further analyses (responses in other time windows prior to the last TMS pulse were not excluded).
Gene_expression (pulse) of TMS associated with transcranial magnetic stimulation
18) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0 Pain Relevance 0.37
Importantly, this TMS-induced right fronto-parietal network effect was only found during TMS over right, but not left, PPC and only during active visuospatial judgment.
Neg (not) Gene_expression (left) of TMS-induced in PPC associated with transcranial magnetic stimulation
19) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0.09 Pain Relevance 0.44
First, were the remote effects in right MFG during TMS over right PPC really functionally relevant for behavior?
Gene_expression (right) of TMS in PPC associated with transcranial magnetic stimulation
20) Confidence 0.57 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2789405 Disease Relevance 0.05 Pain Relevance 0.42

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